5-氨基酮戊酸荧光引导下的脊髓脑膜瘤切除术
5-Aminolevulinic acid fluorescence-guided surgery for spinal meningioma.
机构信息
Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland.
出版信息
World Neurosurg. 2013 Jul-Aug;80(1-2):223.e1-3. doi: 10.1016/j.wneu.2012.12.017. Epub 2012 Dec 13.
OBJECTIVE
Fluorescence-guided surgery for cranial meningioma has been reported to be useful. There are no reports about spinal cases using this technique. We report on a meningioma of the cervical spine for which fluorescence-guided surgery was used.
CASE DESCRIPTION
A 78-year-old female patient with a meningioma located in the cervical spine underwent surgery using fluorescence guidance. After complete removal of the meningioma and removal and coagulation of the dural attachment (equal to Simpson grade II resection), a fluorescence-positive remnant could be identified and successfully removed. The remnant was found to harbor meningioma tissue on histological examination.
CONCLUSIONS
Fluorescence-guided microsurgery is helpful in achieving a total resection of spinal meningiomas, and might therefore reduce the risk of recurrence.
目的
荧光引导手术在颅脑膜瘤中的应用已被证实是有效的。但目前尚无关于使用该技术治疗脊髓脑膜瘤的报道。我们报告了一例使用该技术治疗的颈椎脑膜瘤病例。
病例描述
一位 78 岁的女性患者患有颈椎脑膜瘤，接受了荧光引导手术。在彻底切除脑膜瘤并切除和凝固硬脑膜附着处（相当于 Simpson 分级 II 切除）后，可识别并成功切除荧光阳性的残留部分。组织学检查发现残留部分含有脑膜瘤组织。
结论
荧光引导显微镜手术有助于实现脊髓脑膜瘤的完全切除，因此可能降低复发风险。
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