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儿童重复腺样体切除术的病例对照研究。

A case-control study of repeated adenoidectomy in children.

机构信息

Departments of Otolaryngology, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

JAMA Otolaryngol Head Neck Surg. 2013 Jan;139(1):32-6. doi: 10.1001/jamaoto.2013.1060.

Abstract

OBJECTIVES

To determine the rate of repeated adenoidectomy in children and examine the risk factors associated with this condition. DESIGN A retrospective nested case-control study was performed. All cases of adenoidectomy performed at a single pediatric institution between 1990 and 2010 were examined. A total of 168 children who had undergone a repeated adenoidectomy were identified. A 1:1 matched case-control study was performed. The data were analyzed using a conditional logistic analysis.

SETTING

Single tertiary pediatric institution.

PATIENTS

Children aged 0 to 18 years having undergone at least 1 adenoidectomy.

MAIN OUTCOME MEASURES

Risk factors associated with repeated adenoidectomy.

RESULTS

A total of 10 948 adenoidectomies were performed in the study period. The rate of repeated adenoidectomy was 1.5% (168 cases). The mean age at first adenoidectomy was significantly lower in the repeated adenoidectomy group (P < .001), and children younger than 5 years at the time of adenoidectomy were 2.5 times more likely to require a repeated procedure. The case-control study identified a strong association between adenoidectomy without tonsillectomy and repeated adenoidectomy, with children who had undergone a repeated adenoidectomy having a 3.68-times higher odds (95% CI, 2.10-6.45) of having an adenoidectomy alone.

CONCLUSIONS

Age younger than 5 years and adenoidectomy without tonsillectomy were identified as important risk factors for repeated adenoidectomy in children. Parents should be made aware of the increased risk of adenoid regrowth if surgery is performed at a young age. Children undergoing adenoidectomy alone should be followed up carefully to monitor for symptom recurrence.

摘要

目的

确定儿童腺样体切除术的重复率,并探讨与该情况相关的危险因素。

设计

回顾性巢式病例对照研究。检查了 1990 年至 2010 年期间在一家儿科机构进行的所有腺样体切除术病例。共确定了 168 例接受重复腺样体切除术的儿童。进行了 1:1 匹配的病例对照研究。使用条件逻辑分析对数据进行分析。

地点

单一的三级儿科机构。

患者

年龄在 0 至 18 岁之间,至少接受过 1 次腺样体切除术的儿童。

主要观察指标

与重复腺样体切除术相关的危险因素。

结果

在研究期间共进行了 10948 例腺样体切除术。重复腺样体切除术的发生率为 1.5%(168 例)。首次腺样体切除术的平均年龄在重复腺样体切除术组中明显较低(P<0.001),腺样体切除术时年龄小于 5 岁的儿童再次手术的可能性增加 2.5 倍。病例对照研究发现,腺样体切除术不伴扁桃体切除术与重复腺样体切除术之间存在很强的关联,再次行腺样体切除术的儿童其单独行腺样体切除术的几率增加 3.68 倍(95%CI,2.10-6.45)。

结论

年龄小于 5 岁和腺样体切除术不伴扁桃体切除术是儿童重复腺样体切除术的重要危险因素。如果在年幼时进行手术,应让家长意识到腺样体再次生长的风险增加。应仔细随访行单纯腺样体切除术的儿童,以监测症状复发。

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