Department of Neuropediatrics, University of Giessen, Giessen, Germany.
Epileptic Disord. 2012 Dec;14(4):418-21. doi: 10.1684/epd.2012.0540.
Persistent singultus is a rare condition, occasionally caused by central nervous system abnormalities. We report a six-year-old girl with daily hiccup events. A polygraphic recording capturing nine singultus episodes showed myoclonia of the diaphragm lasting 104-131 milliseconds, time-locked to bilateral, synchronous, double-spike-and-wave discharges, maximum at frontal contacts. The initial EEG spikes preceded the onset of EMG discharges by 56-64 (median: 59) milliseconds. This is the first description of an epileptic patient with hiccups as the main seizure manifestation. The electrophysiological findings suggest a primary generalised form of epilepsy and polysynaptic impulse transmission. [Published with video sequences].
持续性呃逆是一种罕见的情况，偶尔由中枢神经系统异常引起。我们报告了一例六岁女孩，每天发生呃逆事件。一项多导睡眠记录捕捉到了九次呃逆发作，显示膈肌肌阵挛持续 104-131 毫秒，与双侧、同步、双棘波和尖波放电时间锁定，在额部接触处达到最大值。初始 EEG 棘波在前肌电放电开始前 56-64（中位数：59）毫秒出现。这是首例以呃逆为主要发作表现的癫痫患者的电生理描述。电生理发现提示原发性全身性癫痫和多突触冲动传递。[发表时附有视频序列]。
