Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK.
BMJ. 2012 Dec 14;345:e8012. doi: 10.1136/bmj.e8012.
To assess the diagnostic accuracy of pain on travelling over speed bumps for the diagnosis of acute appendicitis.
Prospective questionnaire based diagnostic accuracy study.
Secondary care surgical assessment unit at a district general hospital in the UK.
101 patients aged 17-76 years referred to the on-call surgical team for assessment of possible appendicitis.
Sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios for pain over speed bumps in diagnosing appendicitis, with histological diagnosis of appendicitis as the reference standard.
The analysis included 64 participants who had travelled over speed bumps on their journey to hospital. Of these, 34 had a confirmed histological diagnosis of appendicitis, 33 of whom reported increased pain over speed bumps. The sensitivity was 97% (95% confidence interval 85% to 100%), and the specificity was 30% (15% to 49%). The positive predictive value was 61% (47% to 74%), and the negative predictive value was 90% (56% to 100%). The likelihood ratios were 1.4 (1.1 to 1.8) for a positive test result and 0.1 (0.0 to 0.7) for a negative result. Speed bumps had a better sensitivity and negative likelihood ratio than did other clinical features assessed, including migration of pain and rebound tenderness.
Presence of pain while travelling over speed bumps was associated with an increased likelihood of acute appendicitis. As a diagnostic variable, it compared favourably with other features commonly used in clinical assessment. Asking about speed bumps may contribute to clinical assessment and could be useful in telephone assessment of patients.
评估在通过减速带时出现疼痛对诊断急性阑尾炎的诊断准确性。
前瞻性基于问卷的诊断准确性研究。
英国一家地区综合医院的二级保健外科评估单位。
101 名年龄在 17-76 岁之间的患者,因疑似阑尾炎被转至值班外科团队进行评估。
在诊断阑尾炎方面,减速带疼痛的敏感度、特异度、阳性预测值、阴性预测值、阳性似然比和阴性似然比,以阑尾炎的组织学诊断为参考标准。
对 64 名在前往医院途中通过减速带的参与者进行了分析。其中 34 人有明确的组织学阑尾炎诊断,其中 33 人报告在通过减速带时疼痛加剧。敏感度为 97%(95%置信区间 85%至 100%),特异度为 30%(15%至 49%)。阳性预测值为 61%(47%至 74%),阴性预测值为 90%(56%至 100%)。阳性试验结果的可能性比为 1.4(1.1 至 1.8),阴性结果的可能性比为 0.1(0.0 至 0.7)。减速带的敏感度和阴性似然比优于其他评估的临床特征,包括疼痛转移和反跳痛。
在通过减速带时出现疼痛与急性阑尾炎的可能性增加有关。作为一个诊断变量,它与临床评估中常用的其他特征相比具有优势。询问减速带相关情况可能有助于临床评估,并且在对患者进行电话评估时可能有用。