青少年炎症性肠病的行为功能：感知障碍作为药物依从性的中介。
Behavioral functioning in youth with inflammatory bowel disease: perceived barriers as mediator of medication adherence.
机构信息
Department of Psychology, University of Georgia, Athens, GA 30602-3013, USA.
出版信息
J Pediatr Psychol. 2013 Apr;38(3):309-20. doi: 10.1093/jpepsy/jss122. Epub 2012 Dec 17.
OBJECTIVES
To examine the relationship between behavioral functioning specific to levels of attention and conduct problems and prescription medication adherence in youth with inflammatory bowel disease (IBD), and examine the mediational role of perceived barriers to adherence. Identifying potentially malleable factors associated with poor adherence such as behavioral functioning and barriers may guide treatment.
METHODS
85 adolescents with IBD and their parents completed measures of adherence, attention and conduct problems, and barriers. To examine mediation models, indirect effects were tested using bootstrapping procedures outlined by Preacher & Hayes (2004, 2008).
RESULTS
The majority of participants reported normative levels of attention and conduct problems. Higher levels of attention problems, conduct problems, and barriers were negatively associated with adherence. Bootstrapping procedures indicated that barriers mediated the effects of behavioral functioning on adherence.
CONCLUSIONS
Barriers may be a proximal factor contributing to the relationship between everyday behavioral functioning and adherence in youth with IBD.
目的
研究青少年炎症性肠病（IBD）中注意力和行为问题特定水平与处方药物依从性之间的关系，并检验依从性障碍的中介作用。识别与依从性差相关的潜在可塑因素，如行为功能和障碍，可能为治疗提供指导。
方法
85 名 IBD 青少年及其父母完成了依从性、注意力和行为问题以及障碍的测量。为了检验中介模型，使用 Preacher 和 Hayes（2004、2008）提出的自举程序检验间接效应。
结果
大多数参与者报告了正常的注意力和行为问题水平。较高的注意力问题、行为问题和障碍与依从性呈负相关。自举程序表明，障碍中介了行为功能对依从性的影响。
结论
障碍可能是导致青少年 IBD 日常行为功能与依从性之间关系的一个近端因素。
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