Drexel University College of Medicine, Philadelphia, PA 19144, USA.
J Pediatr Psychol. 2013 Apr;38(3):296-308. doi: 10.1093/jpepsy/jss117. Epub 2012 Dec 17.
To examine whether prenatal cocaine exposure (PCE) predicts externalizing problems in late childhood.
Externalizing problems were assessed using caregiver, teacher, and child ratings and a laboratory task when children (N = 179; 74 cocaine exposed) were aged 8-10 years. PCE, environmental risk, sex, neonatal health, other prenatal exposures, and foster care history were examined as predictors of externalizing problems.
Multiple regression analyses indicated that PCE, environmental risk, and male sex explained significant variance in externalizing problems in late childhood. Models varied by source of information. PCE predicted externalizing problems for child laboratory behavior and interacted with sex because males with PCE reported more externalizing problems. PCE did not predict caregiver or teacher ratings of externalizing problems.
The effect of PCE on externalizing problems may persist into late childhood. The findings highlight the potential importance of including child-based measures of externalizing problems in studies of prenatal exposure.
探讨产前可卡因暴露(PCE)是否预测儿童晚期的外化问题。
当儿童(N=179;74 名可卡因暴露)年龄在 8-10 岁时,使用照顾者、教师和儿童评定以及实验室任务评估外化问题。将 PCE、环境风险、性别、新生儿健康、其他产前暴露和寄养史作为外化问题的预测因素进行了研究。
多元回归分析表明,PCE、环境风险和男性性别解释了儿童晚期外化问题的显著差异。模型因信息来源而异。PCE 预测了儿童实验室行为的外化问题,并与性别相互作用,因为有 PCE 的男性报告了更多的外化问题。PCE 不预测照顾者或教师对外化问题的评定。
PCE 对外化问题的影响可能持续到儿童晚期。研究结果强调了在研究产前暴露时纳入儿童外化问题的基于儿童的测量的重要性。