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羊膜移植术治疗手术诱发的坏死性巩膜炎合并周边溃疡性角膜炎

Amniotic membrane transplantation in surgically induced necrotizing scleritis with peripheral ulcerative keratitis.

作者信息

Thatte Shreya, Gupta Lalita

机构信息

Department of Ophthalmology, Sri Aurobindo Institute of Medical Sciences, Indore, Madhya Pradesh, India.

出版信息

Middle East Afr J Ophthalmol. 2012 Oct;19(4):419-21. doi: 10.4103/0974-9233.102765.

Abstract

A case of surgically induced necrotizing scleritis (SINS) after manual small incision cataract surgery that was associated with peripheral ulcerative keratitis (PUK) at a different site. Neither pathology responded to systemic steroids and progressed to become sight threatening, which is unusual. Progression of SINS was aggressive enough to cause a limbal wound gape, similarly PUK extended up to Descemet's membrane and emergency amniotic membrane transplantation (AMT) was required to save the globe. AMT may regress the scleral and corneal melting successfully. It is not common to observe SINS with PUK at a different site that is unresponsive to systemic steroids. AMT, though palliative treatment, was effective at treating this condition successfully.

摘要

1例手法小切口白内障手术后发生手术诱发的坏死性巩膜炎(SINS),并伴有不同部位的周边溃疡性角膜炎(PUK)。两种病变对全身使用类固醇均无反应并进展至威胁视力,这并不常见。SINS进展迅速,导致角膜缘伤口裂开,同样,PUK扩展至后弹力层,需要紧急羊膜移植(AMT)来挽救眼球。AMT可能成功缓解巩膜和角膜的溶解。观察到SINS合并不同部位的PUK且对全身类固醇无反应并不常见。AMT虽是姑息性治疗,但成功有效治疗了这种情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd6d/3519133/d8c3a3c6d9ac/MEAJO-19-419-g001.jpg

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