Kumar K Jagadish, Suryaprakash H, Manjunath V G, Harsha S
Department of Pediatrics, JSS Medical College, JSS University, Mysore, Karnataka, India.
J Pediatr Neurosci. 2012 May;7(2):117-9. doi: 10.4103/1817-1745.102573.
Infantile Alexander disease (AD) is a rare leukodystrophy characterized by its early onset within 2 years of life and clinically presents with macrocephaly, seizures, and retarded psychomotor development. Magnetic resonance imaging (MRI) shows characteristic symmetric white matter abnormalities with frontal predominance. We present a case of infantile AD with typical clinical characteristics and MRI features.
婴儿型亚历山大病（AD）是一种罕见的脑白质营养不良，其特征为在2岁内发病，临床上表现为巨头畸形、癫痫发作和精神运动发育迟缓。磁共振成像（MRI）显示特征性的以额叶为主的对称性白质异常。我们报告一例具有典型临床特征和MRI表现的婴儿型AD病例。
