Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, ON, Canada.
Expert Rev Mol Diagn. 2012 Nov;12(8):831-40. doi: 10.1586/erm.12.118.
A new wave of rapid and accurate molecular diagnostics, which harness the power of genomics and proteomics, hold great potential to improve aspects of maternal health on a global scale. This review will provide a context to issues related to global maternal health and highlight international endeavors aimed to alleviate morbidity and mortality during pregnancy, childbirth and into the postnatal period. The authors will couple these efforts to actionable and promising theranostic advancements in the detection and treatment of HIV and malaria through the lens of maternal global health strategies.
一波新的快速而准确的分子诊断技术正在涌现,这些技术利用基因组学和蛋白质组学的力量,具有极大的潜力来改善全球范围内的母婴健康状况。本综述将提供与全球母婴健康相关问题的背景,并强调旨在减轻妊娠、分娩和产后期间发病率和死亡率的国际努力。作者将通过母婴全球健康战略的视角,将这些努力与 HIV 和疟疾的检测和治疗方面的可行且有前途的治疗诊断进展相结合。