Hoyoux C, Forget P, Piette C, Dresse M F, Florkin B, Rausin L, Thiry A
Pediatric Hematology-Oncology, CHR Citadelle, Boulevard 12ème de ligne, 4000 Liege, Belgium.
Case Rep Med. 2012;2012:891714. doi: 10.1155/2012/891714. Epub 2012 Nov 24.
Paravertebral malignant tumors constitute 4.8% of cancer cases in pediatric oncology and are mostly composed of neuroblastoma (46.4%) and soft tissue sarcomas (35.7%). We describe the case of a Caucasian 6-year-old boy who was admitted for middle back pain radiated to limbs and progressively increasing weakness of the legs, suggesting a spinal cord disease. The exploration revealed two paravertebral masses extending through the neural foraminae into the epidural space. The association with elevated serum neuron specific enolase suggested at first the diagnosis of neuroblastoma, but the pathological examination revealed a Burkitt's lymphoma. This is a rare location of sporadic Burkitt's lymphoma with neurologic syndrome as first symptoms.
椎旁恶性肿瘤占小儿肿瘤病例的4.8%,主要由神经母细胞瘤(46.4%)和软组织肉瘤(35.7%)组成。我们描述了一名6岁白人男孩的病例,他因中背部疼痛放射至四肢且腿部无力逐渐加重而入院,提示脊髓疾病。检查发现两个椎旁肿块通过神经孔延伸至硬膜外间隙。血清神经元特异性烯醇化酶升高起初提示神经母细胞瘤诊断,但病理检查显示为伯基特淋巴瘤。这是散发性伯基特淋巴瘤罕见的发病部位,以神经综合征为首发症状。