抗苗勒管激素评估子宫内膜异位症腹腔镜囊肿切除术女性的卵巢储备功能。

Ovarian reserve evaluation by anti-mullerian hormone in women undergoing laparoscopic cystectomy of endometrioma.

作者信息

Suksompong Singpetch, Dejarkom Surachai, Petyim Somsin, Dangrat Chongdee, Orachon Daunpen, Choavaratana Roungsin

机构信息

Infertility Unit, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2012 Nov;95(11):1389-95.

PMID:23252204

Abstract

OBJECTIVE

To study the serial changes of serum AMH to determine ovarian reserve recovery after laparoscopic cystectomy of endometrioma.

MATERIAL AND METHOD

Forty-three endometrioma patients who underwent laparoscopic cystectomy of endometrioma were tested for levels of serum AMH at preoperation, 1 week, and 3 months postoperation.

RESULTS

Median serum AMH was 2.11 ng/mL (range = 0.22 to 9.24 ng/mL) before surgery. This level also reduced at first week postoperation (p < 0.01) but did not reach a significant difference between the first week and the third month (1.02 ng/mL and 1.06 ng/mL, respectively). The recovery rate of AMH level in unilateral endometrioma was higher than bilateral endometrioma (32.4% vs. -3.6%, p = 0.02).

CONCLUSION

Ovarian reserve was decreased after laparoscopic cystectomy of endometrioma and did not significantly restore after three months of postoperation. The recovery of ovarian reserve after unilateral endometriotic cystectomy was faster than that after bilateral endometriotic cystectomy.

摘要

目的

研究血清抗缪勒管激素（AMH）的系列变化，以确定子宫内膜异位囊肿腹腔镜切除术后卵巢储备功能的恢复情况。

材料与方法

对43例行子宫内膜异位囊肿腹腔镜切除术的患者，在术前、术后1周及术后3个月检测血清AMH水平。

结果

术前血清AMH中位数为2.11 ng/mL（范围=0.22至9.24 ng/mL）。术后第1周该水平也降低（p<0.01），但第1周与第3个月之间无显著差异（分别为1.02 ng/mL和1.06 ng/mL）。单侧子宫内膜异位囊肿患者AMH水平的恢复率高于双侧患者（32.4%对-3.6%，p=0.02）。