Galway Medical Technologies Centre-GMedTech, Department of Mechanical and Industrial Engineering, Galway Mayo Institute of Technology, Galway, Ireland.
Int J Numer Method Biomed Eng. 2013 Feb;29(2):179-96. doi: 10.1002/cnm.2525. Epub 2012 Dec 18.
Endovascular repair is now a recognised procedure for treating abdominal aortic aneurysms. However, post-operative complications such as stent graft migration and thrombus may still occur. To assess these complications numerically, the correct input boundary conditions, which include the full human aorta with associated branching, should be included. Four patient-specific computed tomography scanned bifurcated stent grafts (SGs) were modelled and attached onto a full human aorta, which included the ascending, aortic arch and descending aortas. Two of the SG geometries had a twisted leg configuration, while the other two had conventional nontwisted leg configurations. Computational fluid dynamics was completed for both geometries and the hemodynamics assessed. The complexity of the flow patterns and secondary flows were influenced by the inclusion of the full human aorta at the SG proximal section. During the decelerating phase significant recirculations occurred along the main body of all SG configurations. The inclusion of the full human aorta did not impact the velocity contours within the distal legs and there was no difference in drag forces with the SG containing the full human aorta and those without. A twisted leg configuration further promoted a spiral flow formation along its distal legs.
血管内修复术现在是治疗腹主动脉瘤的一种公认的方法。然而,支架移植物迁移和血栓等术后并发症仍可能发生。为了对这些并发症进行数值评估,应包括完整的人体主动脉及其相关分支作为正确的输入边界条件。对四个特定于患者的分叉支架移植物(SG)进行了建模,并将其连接到包括升主动脉、主动脉弓和降主动脉的完整人体主动脉上。两个 SG 几何形状具有扭曲的腿部结构,而另外两个具有常规的非扭曲腿部结构。对两种几何形状都进行了计算流体动力学分析,并评估了血液动力学。在 SG 近端部分包括完整的人体主动脉会影响流动模式和二次流动的复杂性。在减速阶段,所有 SG 构型的主体都会发生明显的回流。包括完整的人体主动脉不会影响远端腿部的速度轮廓,并且包含完整人体主动脉的 SG 和不包含完整人体主动脉的 SG 在阻力方面没有差异。扭曲的腿部结构进一步促进了其远端腿部的螺旋流动形成。