通过钌（II）催化烯胺的 C-H 键功能化实现多功能吡咯合成。

Versatile pyrrole synthesis through ruthenium(II)-catalyzed alkene C-H bond functionalization on enamines.

机构信息

Institut für Organische und Biomolekulare Chemie, Georg-August-Universität, Tammannstrasse 2, 37077 Göttingen, Germany.

出版信息

Org Lett. 2013 Jan 4;15(1):176-9. doi: 10.1021/ol303224e. Epub 2012 Dec 20.

Abstract

An efficient ruthenium(II) catalyst enabled broadly applicable oxidative alkyne annulations with electron-rich enamines to provide diversely decorated pyrroles, even in an aerobic fashion with air as the ideal oxidant.

摘要

一种高效的钌（II）催化剂能够实现广泛适用的氧化炔烃环化反应，与富电子烯胺反应，提供多种官能化的吡咯，甚至可以在有氧条件下，以空气为理想氧化剂。

相似文献

Versatile pyrrole synthesis through ruthenium(II)-catalyzed alkene C-H bond functionalization on enamines.

Org Lett. 2013 Jan 4;15(1):176-9. doi: 10.1021/ol303224e. Epub 2012 Dec 20.

Ruthenium-catalyzed pyrrole synthesis via oxidative annulation of enamides and alkynes.

Org Lett. 2013 Jan 4;15(1):136-9. doi: 10.1021/ol303159h. Epub 2012 Dec 12.

Carboxylate-assisted ruthenium-catalyzed alkyne annulations by C-H/Het-H bond functionalizations.

Acc Chem Res. 2014 Feb 18;47(2):281-95. doi: 10.1021/ar3002798. Epub 2013 Feb 4.

One-pot silver-catalyzed and PIDa-mediated sequential reactions: synthesis of polysubstituted pyrroles directly from alkynoates and amines.

Org Lett. 2010 Jan 15;12(2):312-5. doi: 10.1021/ol9026478.

Versatile synthesis of isocoumarins and α-pyrones by ruthenium-catalyzed oxidative C-H/O-H bond cleavages.

Org Lett. 2012 Feb 3;14(3):930-3. doi: 10.1021/ol2034614. Epub 2012 Jan 24.

Ruthenium-catalyzed oxidative synthesis of 2-pyridones through C-H/N-H bond functionalizations.

Org Lett. 2011 Jun 17;13(12):3278-81. doi: 10.1021/ol201244s. Epub 2011 May 25.

Ruthenium(II)-catalyzed C-H activation/alkyne annulation by weak coordination with O2 as the sole oxidant.

Angew Chem Int Ed Engl. 2015 Apr 27;54(18):5513-7. doi: 10.1002/anie.201500600. Epub 2015 Mar 3.

Hydroxyl-directed ruthenium-catalyzed C-H bond functionalization: versatile access to fluorescent pyrans.

Org Lett. 2012 Jul 6;14(13):3416-9. doi: 10.1021/ol301387t. Epub 2012 Jun 12.

Pyrrole synthesis via allylic sp3 C-H activation of enamines followed by intermolecular coupling with unactivated alkynes.

J Am Chem Soc. 2010 Jul 21;132(28):9585-7. doi: 10.1021/ja104305s.

Cationic ruthenium catalysts for alkyne annulations with oximes by C-H/N-O functionalizations.

J Org Chem. 2012 Oct 19;77(20):9190-8. doi: 10.1021/jo301768b. Epub 2012 Sep 27.

引用本文的文献

Tandem Cu(I)-Catalyzed Dipolar Cycloaddition-C-H Activation for the In-Flow Synthesis of -Pyridyl-5-amino-1,2,3-triazole-4-carboxylates.

Org Lett. 2025 May 2;27(17):4423-4427. doi: 10.1021/acs.orglett.5c00453. Epub 2025 Apr 18.

Bifurcated Rhodaelectro-catalyzed C-H Activation for the Synthesis of Pyrroles and Lactones.

Precis Chem. 2023 Jul 20;1(6):382-387. doi: 10.1021/prechem.3c00061. eCollection 2023 Aug 28.

Synthesis of unsymmetrically tetrasubstituted pyrroles and studies of AIEE in pyrrolo[1,2-]pyrimidine derivatives.

Chem Sci. 2022 Apr 20;13(19):5667-5673. doi: 10.1039/d2sc00837h. eCollection 2022 May 18.

Progress and prospects in copper-catalyzed C-H functionalization.

RSC Adv. 2020 Sep 17;10(57):34429-34458. doi: 10.1039/d0ra06518h. eCollection 2020 Sep 16.

Iodine-catalyzed diazo activation to access radical reactivity.

Nat Commun. 2018 May 17;9(1):1972. doi: 10.1038/s41467-018-04331-4.

Rh-catalyzed aerobic oxidative cyclization of anilines, alkynes, and CO.

Chem Sci. 2017 Sep 1;8(9):6266-6273. doi: 10.1039/c7sc02181j. Epub 2017 Jul 3.

Direct Synthesis of Highly Substituted Pyrroles and Dihydropyrroles Using Linear Selective Hydroacylation Reactions.

Chemistry. 2016 Jun 1;22(23):7879-84. doi: 10.1002/chem.201600311. Epub 2016 Apr 23.

A mild and efficient AgSbF-catalyzed synthesis of fully substituted pyrroles through a sequential propargylation/amination/cycloisomerization reaction.

Tetrahedron. 2014 Aug 26;70(34):5267-5273. doi: 10.1016/j.tet.2014.05.073.

Catalytic 1,4-rhodium(III) migration enables 1,3-enynes to function as one-carbon oxidative annulation partners in C-H functionalizations.

Angew Chem Int Ed Engl. 2014 Sep 8;53(37):9931-5. doi: 10.1002/anie.201406072. Epub 2014 Jul 22.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

通过钌（II）催化烯胺的 C-H 键功能化实现多功能吡咯合成。

Versatile pyrrole synthesis through ruthenium(II)-catalyzed alkene C-H bond functionalization on enamines.

机构信息

出版信息

相似文献

引用本文的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

通过钌（II）催化烯胺的 C-H 键功能化实现多功能吡咯合成。

Versatile pyrrole synthesis through ruthenium(II)-catalyzed alkene C-H bond functionalization on enamines.

机构信息

出版信息

相似文献

引用本文的文献