Lam Allen, Holbrook Eric
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA.
Adv Otorhinolaryngol. 2013;74:1-11. doi: 10.1159/000342263. Epub 2012 Dec 18.
The skull base is an intricate interface between the cranium and face allowing the passageway of vital structures. Anatomic conceptualization forms the platform for surgical approaches and solutions to skull base pathology. Understanding embryogenesis provides further depth into the pathophysiology of congenital defects. This chapter aims to highlight skull base anatomy and embryology along with cerebrospinal fluid physiology and diagnostic evaluation of cerebrospinal fluid leaks.
颅底是颅骨与面部之间一个复杂的界面，允许重要结构通过。解剖学概念为颅底病变的手术入路和解决方案奠定了基础。了解胚胎发育有助于更深入地理解先天性缺陷的病理生理学。本章旨在重点介绍颅底解剖学和胚胎学，以及脑脊液生理学和脑脊液漏的诊断评估。
