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动情期或动情后期大鼠下腹神经传入纤维对子宫扩张的反应。

Responses of hypogastric nerve afferent fibers to uterine distension in estrous or metestrous rats.

作者信息

Robbins A, Sato Y, Hotta H, Berkley K J

机构信息

Tokyo Metropolitan Institute of Gerontology, Department of Physiology, Japan.

出版信息

Neurosci Lett. 1990 Mar 2;110(1-2):82-5. doi: 10.1016/0304-3940(90)90791-7.

DOI:10.1016/0304-3940(90)90791-7
PMID:2325894
Abstract

The response of afferent fibers in the distal end of the cut hypogastric nerve to distension of the uterus to various pressure levels was investigated in anesthetized virgin female rats on two different days of the estrous cycle (estrus or metestrus). Whereas relatively intense levels of uterine distension produced an increase in afferent activity in a pressure-dependent manner in both stages of the estrous cycle, the minimal pressure necessary to activate the fibers was significantly less on the day of estrus. These results suggest that hypogastric nerve afferent fibers are more likely to respond to potentially damaging uterine stimuli during the time when such responsiveness would be most important for reproductive success.

摘要

在发情周期的两个不同日子(发情期或动情后期),对麻醉状态下的未交配雌性大鼠,研究了切断的腹下神经远端传入纤维对子宫不同压力水平扩张的反应。在发情周期的两个阶段,相对较高强度的子宫扩张均以压力依赖方式使传入活动增加,然而,激活这些纤维所需的最小压力在发情期显著更低。这些结果表明,在对生殖成功最为重要的时期,腹下神经传入纤维更易对潜在损伤性的子宫刺激作出反应。

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