异基因造血干细胞移植受者的鲍曼不动杆菌败血症
Acinetobacter baumannii Septicemia in a Recipient of an Allogeneic Hematopoietic Stem Cell Transplantation.
作者信息
Al-Anazi Khalid Ahmed, Abdalhamid Baha, Alshibani Zeyad, Awad Khalid, Alzayed Abdullah, Hassan Hoda, Alsayiegh Mohammed
机构信息
Section of Adult Hematology and Hematopoietic, Stem Cell Transplant, Oncology Center, King Fahad Specialist Hospital, P.O. Box 15215, Dammam 31444, Saudi Arabia.
出版信息
Case Rep Transplant. 2012;2012:646195. doi: 10.1155/2012/646195. Epub 2012 Aug 7.
Abstract
Acinetobacter baumannii is a gram-negative, nonfermentative coccobacillus that causes infections in immunocompromised and chronically ill patients and is associated with multidrug resistance. Two days before receiving her nonmyeloablative stem cell allograft, a patient with acute myeloid leukemia developed Acinetobacter baumannii bacteremia that caused septic shock which was successfully treated with imipenem and removal of the central venous catheter. To our knowledge, this is the first report of Acinetobacter baumannii septicemia in a hematopietic stem cell transplantation recipient.
摘要
鲍曼不动杆菌是一种革兰氏阴性、非发酵的球杆菌，可导致免疫功能低下和慢性病患者感染，且与多重耐药性相关。一名急性髓系白血病患者在接受非清髓性干细胞同种异体移植前两天发生了鲍曼不动杆菌菌血症，导致感染性休克，通过亚胺培南治疗及拔除中心静脉导管后成功治愈。据我们所知，这是造血干细胞移植受者中鲍曼不动杆菌败血症的首例报告。
相似文献
1
Acinetobacter baumannii Septicemia in a Recipient of an Allogeneic Hematopoietic Stem Cell Transplantation.异基因造血干细胞移植受者的鲍曼不动杆菌败血症
Case Rep Transplant. 2012;2012:646195. doi: 10.1155/2012/646195. Epub 2012 Aug 7.
2
Roseomonas bacteremia in a recipient of an allogeneic hematopoietic stem cell transplantation.异基因造血干细胞移植受者的玫瑰单胞菌血症
Transpl Infect Dis. 2013 Aug;15(4):E144-7. doi: 10.1111/tid.12100. Epub 2013 Jun 3.
3
Infections Caused by Acinetobacter baumannii in Recipients of Hematopoietic Stem Cell Transplantation.造血干细胞移植受者中鲍曼不动杆菌引起的感染
Front Oncol. 2014 Jul 14;4:186. doi: 10.3389/fonc.2014.00186. eCollection 2014.
4
Septic shock caused by Sphingomonas paucimobilis bacteremia in a patient with hematopoietic stem cell transplantation.造血干细胞移植患者中少动鞘氨醇单胞菌血症所致的感染性休克
Transpl Infect Dis. 2008 Apr;10(2):142-4. doi: 10.1111/j.1399-3062.2007.00262.x. Epub 2007 Jul 1.
5
Incidence and risk factors for carbapenem- and multidrug-resistant Acinetobacter baumannii bacteremia in hematopoietic stem cell transplantation recipients.造血干细胞移植受者中碳青霉烯类耐药和多重耐药鲍曼不动杆菌血症的发病率及危险因素
Scand J Infect Dis. 2014 Feb;46(2):81-8. doi: 10.3109/00365548.2013.857042. Epub 2013 Dec 11.
6
Successful organ transplantation from donors with Acinetobacter baumannii septic shock.成功地从患有鲍曼不动杆菌败血症休克的供体进行器官移植。
Transplantation. 2006 Mar 27;81(6):853-5. doi: 10.1097/01.tp.0000203804.95180.6e.
7
Resistance: A Real Challenge for Clinicians.耐药性：临床医生面临的真正挑战。
Antibiotics (Basel). 2020 Apr 23;9(4):205. doi: 10.3390/antibiotics9040205.
8
[Acinetobacter baumannii: an important pathogen with multidrug resistance in newborns].鲍曼不动杆菌：新生儿中一种具有多重耐药性的重要病原菌
Mikrobiyol Bul. 2011 Oct;45(4):716-22.
9
Eradication of multidrug-resistant Acinetobacter baumannii in a female patient with total hip arthroplasty, with debridement and retention: a case report.1例全髋关节置换术后女性患者多药耐药鲍曼不动杆菌的清除：清创并保留假体的病例报告
J Med Case Rep. 2009 Feb 3;3:45. doi: 10.1186/1752-1947-3-45.
10
Characteristics of invasive Acinetobacter infection: A multicenter investigation with molecular identification of causative organisms.侵袭性不动杆菌感染的特征：一项多中心调查及病原菌的分子鉴定。
J Infect Chemother. 2020 May;26(5):475-482. doi: 10.1016/j.jiac.2019.12.010. Epub 2020 Jan 7.
引用本文的文献
1
Hybrid Genome and Clinical Impact of Emerging Extensively Drug-Resistant Priority Bacterial Pathogen in Saudi Arabia.沙特阿拉伯新出现的广泛耐药重点细菌病原体的混合基因组及临床影响
Life (Basel). 2025 Jul 12;15(7):1094. doi: 10.3390/life15071094.
2
Emerging Status of Multidrug-Resistant Bacteria and Fungi in the Arabian Peninsula.阿拉伯半岛多重耐药细菌和真菌的新出现情况。
Biology (Basel). 2021 Nov 6;10(11):1144. doi: 10.3390/biology10111144.
3
Prevalence of Acinetobacter baumannii in Saudi Arabia: risk factors, antimicrobial resistance patterns and mechanisms of carbapenem resistance.沙特阿拉伯鲍曼不动杆菌的流行情况：危险因素、抗菌药物耐药模式和碳青霉烯类耐药机制。
Ann Clin Microbiol Antimicrob. 2019 Jan 3;18(1):1. doi: 10.1186/s12941-018-0301-x.
4
Acinetobacter baumannii bacteraemia in patients with haematological malignancy: a multicentre retrospective study from the Infection Working Party of Jiangsu Society of Hematology.血液系统恶性肿瘤患者鲍曼不动杆菌败血症：江苏省血液学学会感染工作组的多中心回顾性研究
Eur J Clin Microbiol Infect Dis. 2017 Jul;36(7):1073-1081. doi: 10.1007/s10096-016-2895-2. Epub 2017 Jan 18.
5
A prospective evaluation of synergistic effect of sulbactam and tazobactam combination with meropenem or colistin against multidrug resistant Acinetobacter baumannii.舒巴坦和他唑巴坦与美罗培南或黏菌素联合使用对多重耐药鲍曼不动杆菌协同作用的前瞻性评估。
Bosn J Basic Med Sci. 2015 Oct 14;15(4):24-9. doi: 10.17305/bjbms.2015.526.
6
Bacterial Infections in Hematopoietic Stem Cell Transplant Recipients.造血干细胞移植受者的细菌感染。
Mediterr J Hematol Infect Dis. 2015 Jul 1;7(1):e2015045. doi: 10.4084/MJHID.2015.045. eCollection 2015.
7
Infections Caused by Acinetobacter baumannii in Recipients of Hematopoietic Stem Cell Transplantation.造血干细胞移植受者中鲍曼不动杆菌引起的感染
Front Oncol. 2014 Jul 14;4:186. doi: 10.3389/fonc.2014.00186. eCollection 2014.
本文引用的文献
1
Prediction of patient outcome from Acinetobacter baumannii bacteremia with Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE) II scores.采用序贯器官衰竭评估（SOFA）和急性生理与慢性健康状况评估（APACHE）II评分预测鲍曼不动杆菌血流感染患者的预后。
Intern Med. 2011;50(8):871-7. doi: 10.2169/internalmedicine.50.4312. Epub 2011 Apr 15.
2
The outcomes of using colistin for treating multidrug resistant Acinetobacter species bloodstream infections.使用黏菌素治疗多重耐药鲍曼不动杆菌血流感染的结果。
J Korean Med Sci. 2011 Mar;26(3):325-31. doi: 10.3346/jkms.2011.26.3.325. Epub 2011 Feb 25.
3
Profile of infections and outcome in high-risk febrile neutropenia: experience from a tertiary care cancer center in India.高危发热性中性粒细胞减少症的感染和结局特征：来自印度一家三级癌症中心的经验。
Med Oncol. 2012 Jun;29(2):1354-60. doi: 10.1007/s12032-011-9858-3. Epub 2011 Feb 20.
4
Multidrug resistant Acinetobacter baumannii: risk factors for appearance of imipenem resistant strains on patients formerly with susceptible strains.多重耐药鲍曼不动杆菌：先前对亚胺培南敏感的患者出现耐亚胺培南菌株的危险因素。
PLoS One. 2010 Apr 1;5(4):e9947. doi: 10.1371/journal.pone.0009947.
5
Treatment of Acinetobacter infections.治疗不动杆菌感染。
Expert Opin Pharmacother. 2010 Apr;11(5):779-88. doi: 10.1517/14656561003596350.
6
The use of carbapenems in the treatment of serious infections.碳青霉烯类药物在严重感染治疗中的应用。
J Intensive Care Med. 2009 Jul-Aug;24(4):230-41. doi: 10.1177/0885066609335660. Epub 2009 Jul 17.
7
Infections in non-myeloablative hematopoietic stem cell transplantation patients with lymphoid malignancies: spectrum of infections, predictors of outcome and proposed guidelines for fungal infection prevention.非清髓性造血干细胞移植患者中发生于淋巴恶性肿瘤的感染：感染谱、结局预测因子和真菌预防感染指南的制订。
Bone Marrow Transplant. 2010 Feb;45(2):339-47. doi: 10.1038/bmt.2009.149. Epub 2009 Jun 29.
8
Treatment of multiresistant Acinetobacter baumannii infections.多重耐药鲍曼不动杆菌感染的治疗
Curr Opin Investig Drugs. 2009 Feb;10(2):150-6.
9
Antimicrobial resistance in Europe and its potential impact on empirical therapy.欧洲的抗菌药物耐药性及其对经验性治疗的潜在影响。
Clin Microbiol Infect. 2008 Dec;14 Suppl 6:2-8. doi: 10.1111/j.1469-0691.2008.02126.x.
10
Acinetobacter baumannii: emergence of a successful pathogen.鲍曼不动杆菌：一种成功病原体的出现
Clin Microbiol Rev. 2008 Jul;21(3):538-82. doi: 10.1128/CMR.00058-07.
Zotero 插件