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异基因造血干细胞移植受者的玫瑰单胞菌血症

Roseomonas bacteremia in a recipient of an allogeneic hematopoietic stem cell transplantation.

作者信息

Al-Anazi K A, AlHashmi H, Abdalhamid B, AlSelwi W, AlSayegh M, Alzayed A, Alshibani Z, AlGarni A, Al-Ghanem A, Hassan H, AlSagheir A

机构信息

Section of Adult Hematology and Hematopoietic Stem Cell Transplant, Oncology Center, King Fahad Specialist Hospital, Dammam, Saudi Arabia.

出版信息

Transpl Infect Dis. 2013 Aug;15(4):E144-7. doi: 10.1111/tid.12100. Epub 2013 Jun 3.

DOI:10.1111/tid.12100
PMID:23725464
Abstract

Roseomonas are pink-pigmented, oxidative, slowly growing, nonfermentative, gram-negative coccobacilli whose identification may require extensive biochemical testing and molecular profiling. Roseomonas infections vary in severity and clinical presentation, and they predominantly occur in immunocompromised and chronically ill patients. The organism is generally susceptible to carbapenems and aminoglycosides, but resistant to most of the cephalosporins and broad-spectrum penicillins. Reported here is a patient with lymphoblastic lymphoma who developed Roseomonas mucosa bacteremia after receiving her hematopoietic stem cell allograft. The bacteremic episode was successfully treated with imipenem and amikacin in addition to removal of the central venous catheter. To our knowledge, this is the first report of Roseomonas bacteremia in a stem cell transplantation recipient.

摘要

玫瑰单胞菌属是一类革兰氏阴性球杆菌,呈粉红色,具有氧化性,生长缓慢,不发酵,其鉴定可能需要广泛的生化检测和分子分析。玫瑰单胞菌感染的严重程度和临床表现各不相同,主要发生在免疫功能低下和慢性病患者中。该菌通常对碳青霉烯类和氨基糖苷类敏感,但对大多数头孢菌素和广谱青霉素耐药。本文报告了一名患有淋巴细胞性淋巴瘤的患者,在接受造血干细胞同种异体移植后发生了黏膜玫瑰单胞菌菌血症。除拔除中心静脉导管外,通过亚胺培南和阿米卡星成功治疗了菌血症发作。据我们所知,这是干细胞移植受者中玫瑰单胞菌菌血症的首例报告。

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Roseomonas mucosa infective endocarditis in patient with systemic lupus erythematosus: case report and review of literature.
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J Ophthalmic Inflamm Infect. 2017 Dec;7(1):5. doi: 10.1186/s12348-017-0123-6. Epub 2017 Jan 28.