Agard E, Malcles A, El Chehab H, Ract-Madoux G, Swalduz B, Aptel F, Denis P, Dot C
Service d'ophtalmologie, HIA Desgenettes, 108, boulevard Pinel, 69003 Lyon, France.
J Fr Ophtalmol. 2013 Apr;36(4):368-71. doi: 10.1016/j.jfo.2012.10.004. Epub 2012 Dec 21.
Iridoschisis is a rare degenerative disease characterized by the separation of the anterior iris stroma from the posterior layer. The anterior layer splits into strands, and the free ends float freely in the anterior chamber. We report the case of a 57-year-old man, in whom we incidentally discovered isolated unilateral iris atrophy. The patient had no history of the common causes of atrophy (herpes, pigment dispersion, ocular trauma, etc.). During follow-up, the atrophy gradually worsened, with an increase in the number and bilaterality of the lesions. Ultrasound biomicroscopy (UBM) and optical coherence tomography (OCT) of anterior chamber showed thinning of the anterior iris and cleavage of the iris into two layers, an imaging result which, to our knowledge, has not yet been reported in the literature. Familiarity with iridoschisis is important, due to its frequent association with glaucoma, so that appropriate screening can be carried out at the time of diagnosis and on follow-up.
虹膜劈裂症是一种罕见的退行性疾病,其特征是前房虹膜基质与后层分离。前层分裂成束状,游离端在前房内自由漂浮。我们报告了一例57岁男性病例,在该病例中我们偶然发现了孤立性单侧虹膜萎缩。患者没有萎缩的常见病因(疱疹、色素播散、眼外伤等)病史。在随访期间,萎缩逐渐加重,病变数量增加且发展为双侧性。前房的超声生物显微镜检查(UBM)和光学相干断层扫描(OCT)显示前房虹膜变薄且虹膜分裂为两层,据我们所知,该影像学结果尚未见文献报道。由于虹膜劈裂症常与青光眼相关,熟悉该疾病对于在诊断时和随访时进行适当的筛查很重要。