Great Ormond Street Hospital for Children NHS Foundation Trust and London South Bank University, London, UK.
Support Care Cancer. 2013 May;21(5):1241-51. doi: 10.1007/s00520-012-1653-y. Epub 2012 Dec 20.
A Delphi study was undertaken to develop a framework guidance that would rationalise and standardise the care of children with febrile neutropenia (FNP) across the UK.
A mailed Delphi survey was undertaken with health professionals working in children's cancer units. The survey employed two rounds of feedback on 22 practice statements drawn from a systematic review of clinical evidence. Consensus was assumed for any statement where 80+ % of respondents indicated that they "agreed" or "strongly agreed".
Consensus was reached on 21 of the 22 practice statements in round 1 that were categorised into six areas: definition of fever and neutropenia, initial management and choice of antibiotic, defining low-risk patients, strategy in low-risk patients and alternative approaches. Consensus could not be reached on whether patients needed to be afebrile to be suitable for discharge and the required length of outpatient antibiotic treatment.
A Delphi survey allowed the successful development of a national framework for identification and management of children with FNP. The use of an existing well-functioning professional network was key in this project's success.
采用德尔菲法研究，制定一个框架指南，以规范和统一英国儿童中性粒细胞减少性发热（FN）的护理。
通过向儿童癌症病房的卫生专业人员邮寄德尔菲调查，对 22 条来自临床证据系统评价的实践声明进行了两轮反馈。任何有 80%+的受访者表示“同意”或“强烈同意”的声明，都被认为达成了共识。
在第一轮中，就 22 个实践声明中的 21 个达成了共识，这些声明被归类为六个方面：发热和中性粒细胞减少的定义、初始管理和抗生素选择、定义低危患者、低危患者的策略和替代方法。对于患者是否需要退热才能适合出院以及门诊抗生素治疗的所需时长，未能达成共识。
德尔菲调查成功制定了一个全国性的框架，用于识别和管理儿童中性粒细胞减少性发热。利用现有的运作良好的专业网络是该项目成功的关键。
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