Louwakul Phumisak, Prucksathamrongkul Wilawan
Department of Restorative Dentistry and Periodontics, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
Pediatr Dent. 2012 Nov-Dec;34(7):e192-6.
The purpose of this study was to evaluate the effect of 2% chlorhexidine gluconate (CHX) compared to normal saline solution (NSS) as an irrigant during pulpectomy in primary molars.
Sixty-four primary mandibular molars from 42 children (average age=5.29±1.45 years old) met the inclusion criteria. CHX or NSS was allocated to each tooth by stratified block randomization. A 1-visit pulpectomy and stainless steel crown were performed by a single investigator. The clinical and radiographic diagnoses were blindly assessed by 2 calibrated investigators.
The overall success rates in the NSS group were approximately 83%, 93%, and 97% at 6, 12, and 18 months, respectively. In the CHX group, the overall success rates were 100%, 97%, and 93% at 6, 12, and 18 months, respectively. Using the chi-square test, the outcomes were significantly different at 6 months, but not significant at 12 and 18 months.
The use of 2% chlorhexidine gluconate in primary molar pulpectomies might enhance the outcome of the treatment 6 months postoperatively. Both normal saline solution and CHX irrigants gave comparable results at longer postoperative periods.
本研究旨在评估在乳牙牙髓摘除术中，与生理盐水溶液（NSS）相比，2%葡萄糖酸氯己定（CHX）作为冲洗剂的效果。
来自42名儿童（平均年龄=5.29±1.45岁）的64颗下颌乳磨牙符合纳入标准。通过分层区组随机化将CHX或NSS分配到每颗牙齿。由一名研究人员进行一次就诊的牙髓摘除术和不锈钢冠修复。由2名经过校准的研究人员对临床和影像学诊断进行盲法评估。
NSS组在6、12和18个月时的总体成功率分别约为83%、93%和97%。在CHX组中，6、12和18个月时的总体成功率分别为100%、97%和93%。使用卡方检验，结果在6个月时差异显著，但在12个月和18个月时不显著。
在乳牙牙髓摘除术中使用2%葡萄糖酸氯己定可能会提高术后6个月的治疗效果。在术后较长时间内，生理盐水溶液和CHX冲洗剂的效果相当。
