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1
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J Neurosurg. 2012 Jan;116(1):122-32. doi: 10.3171/2011.8.JNS101241. Epub 2011 Sep 30.
2
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Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12155-60. doi: 10.1073/pnas.1108107108. Epub 2011 Jun 28.
3
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4
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5
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6
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7
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8
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9
The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins.
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