Child Health Division, Menzies School of Health Research, Charles Darwin University, PO Box 41096, Casuarina, Darwin, Northern Territory 0811, Australia.
J Microbiol Methods. 2013 Mar;92(3):270-2. doi: 10.1016/j.mimet.2012.12.013. Epub 2012 Dec 22.
Correlation was observed between quantitative PCR and semi-quantitative culture for definition of Haemophilus influenzae infection in bronchoalveolar lavage specimens from 81 children with bronchiectasis. However, qPCR data correlated less well with airway neutrophilia, and supports continued use of culture as the gold standard for defining H. influenzae lower airway infection.
在 81 例支气管扩张症患儿的支气管肺泡灌洗液标本中，定量 PCR 与半定量培养在确定流感嗜血杆菌感染方面存在相关性。然而，qPCR 数据与气道中性粒细胞的相关性较差，支持继续将培养作为定义流感嗜血杆菌下呼吸道感染的金标准。
