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可溶性肝细胞癌提取物的纯化

Purification of soluble hepatocellular carcinoma extracts.

作者信息

Lee C S, Chuang C Y, Lin F Y, Lin T Y

出版信息

Zhonghua Min Guo Wei Sheng Wu Xue Za Zhi. 1979 Sep;12(3):81-5.

PMID:232674
Abstract

When soluble hepatocellular carcinoma (HCC) extract prepared by 3 M KCl solution was passed through a column of Sephadex G-200, four fractions (designated as I, II, III, IV) could be obtained from the elution profile. By leukocyte migration inhibition assay, the active component of soluble HCC extract which represented tumor-associated antigen was shown to be contained in fractions I and II.

摘要

当用3M氯化钾溶液制备的可溶性肝细胞癌(HCC)提取物通过Sephadex G - 200柱时,从洗脱图谱中可获得四个级分(分别命名为I、II、III、IV)。通过白细胞迁移抑制试验表明,可溶性HCC提取物中代表肿瘤相关抗原的活性成分包含在级分I和II中。

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