Fischer W, Reichel G, Rabending G, Bruns W, Haubenreiser H, Sodemann K, Zander G
Endokrinologie. 1979;74(3):354-62.
Sensory conduction velocity of the median nerve, motor conduction velocity of both median and tibial nerves, and corresponding distal laterncies are sufficient parameters to establish the diagnosis of polyneuropathy almost with certainty. Considering these six parameters yielded in detection of peripheral nerve dysfunction in 22% of diabetic patients who were free from clinical signs of polyneuropathy. Electroneurographical findings in 340 out of 677 patients with diabetes mellitus were interpreted as evidence of segmental demyelination. Within this group there was the majority of patients with clinical signs of polyneuropathy and with subclinical signs of peripheral nerve dysfunction. There existed a positive correlation between signs of nerve dysfunction with angiopathy, age and duration of the disease. A second group consisting of 243 diabetics with signs of incipient segmental demyelination with or without signs of axonaal degeneration mainly included juvenile patients with a short duration of the disease and with a low frequency of angiopathy.
正中神经感觉传导速度、正中神经和胫神经的运动传导速度以及相应的远端潜伏期是几乎可以肯定地确立多发性神经病诊断的充分参数。考虑这六个参数,在无多发性神经病临床体征的糖尿病患者中,有22%检测到周围神经功能障碍。677例糖尿病患者中有340例的神经电图检查结果被解释为节段性脱髓鞘的证据。在这组患者中,大多数有多发性神经病的临床体征和周围神经功能障碍的亚临床体征。神经功能障碍体征与血管病变、年龄和病程之间存在正相关。第二组由243例有早期节段性脱髓鞘体征(有或无轴突退变体征)的糖尿病患者组成,主要包括病程短且血管病变发生率低的青少年患者。