Nishigaki Takahiko, Okada Kazuyuki, Ebisui Chikara, Wada Yuma, Kato Ryo, Makino Shunichiro, Owada Yoshiyuki, Murakami Masahiro, Yanagisawa Tetsu, Okamura Shu, Murata Kohei, Yokouchi Hideoki, Kinuta Masakatsu
Dept. of Surgery, Suita Muncipal Hospital, Japan.
Gan To Kagaku Ryoho. 2012 Nov;39(12):2107-9.
We report 2 cases of complete response for cStage I(T1bN0M0) esophageal carcinoma treated with chemoradiation therapy. Case 1: A 70-year-old man was diagnosed with cStage I(T1bN0M0) thoracic esophageal carcinoma(Type 0- IIc, squamous cell carcinoma). efinitive chemoradiotherapy (5-FU 250 mg/m2, CDDP 5 mg/m2 days 1-5, 8-12, 15-19, 22-26, 29-33, and 36-40; radiation: 60 Gy/30 Fr) was administrated. After treatment, we confirmed that the esophageal lesion had disappeared by upper endoscopy. Case 2: A 78-year-old man was diagnosed with cStage I(T1bN0M0) thoracic esophageal carcinoma (Type 0-I+IIb, squamous cell carcinoma) and early stage gastric carcinoma. Considering his general condition, radical surgery for esophageal cancer and gastric cancer was difficult; hence, he was treated with definitive chemoradiotherapy. After treatment, the esophageal lesion disappeared and we performed fundusectomy. Chemoradiation therapy appears to be effective for patients with cStage I(T1bN0M0) esophageal carcinoma.
