Ogata M, Shigeta S
Infect Immun. 1979 Nov;26(2):770-4. doi: 10.1128/iai.26.2.770-774.1979.
After infection with varicella-zoster virus, HeLa and human embryo lung cells developed a receptor for the Fc portion of human and rabbit immunoglobulin G. The receptor was detected by both hemadsorption and immunofluorescence, using antibody-coated erythrocytes and heat-aggregated immunoglobulin G. However, sheep erythrocytes sensitized with F(ab')2 of anti-sheep erythrocyte antibody did not adsorb to the receptor. When cell-free varicella-zoster virus was inoculated into the HeLa cell monolayer, the Fc receptor appeared at first 6 h after infection; varicella-zoster virus antigen in the cytoplasm and detectable cytopathic effects appeared later.
感染水痘-带状疱疹病毒后,HeLa细胞和人胚肺细胞产生了针对人及兔免疫球蛋白G Fc段的受体。使用抗体包被的红细胞和热聚集免疫球蛋白G,通过血细胞吸附和免疫荧光检测到了该受体。然而,用抗绵羊红细胞抗体的F(ab')2致敏的绵羊红细胞不会吸附到该受体上。将无细胞水痘-带状疱疹病毒接种到HeLa细胞单层中,Fc受体在感染后6小时首次出现;细胞质中的水痘-带状疱疹病毒抗原和可检测到的细胞病变效应随后出现。