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The metabolism and elimination of cimetidine, a histamine H2-receptor antagonist, in the rat, dog, and man.

作者信息

Taylor D C, Cresswell P R, Bartlett D C

出版信息

Drug Metab Dispos. 1978 Jan-Feb;6(1):21-30.

PMID:23270
Abstract
摘要

相似文献

1
The metabolism and elimination of cimetidine, a histamine H2-receptor antagonist, in the rat, dog, and man.组胺H2受体拮抗剂西咪替丁在大鼠、狗和人体内的代谢与消除。
Drug Metab Dispos. 1978 Jan-Feb;6(1):21-30.
2
Characterization and development of cimetidine as a histamine H2-receptor antagonist.西咪替丁作为组胺H2受体拮抗剂的特性与研发
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3
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Drug Metab Dispos. 1990 Nov-Dec;18(6):949-53.
4
Accumulation of cimetidine by kidney cortex slices.西咪替丁在肾皮质切片中的蓄积。
J Pharmacol Exp Ther. 1982 May;221(2):342-6.
5
Metabolism of labetalol by animals and man.拉贝洛尔在动物和人体内的代谢。
Br J Clin Pharmacol. 1976 Aug;3(4 Suppl 3):695-710.
6
Solubilization of a [3H]cimetidine binding site from rat brains. A clonidine-sensitive H-2 receptor subtype?大鼠脑内[3H]西咪替丁结合位点的增溶作用。一种对可乐定敏感的H-2受体亚型？
Mol Pharmacol. 1981 Sep;20(2):240-3.
7
Disposition of bethanidine, N-benzyl-N',N''-dimethylguanidine, in the rat, dog and man.苄乙胍（N-苄基-N'，N''-二甲基胍）在大鼠、狗和人体内的处置情况。
Drug Metab Dispos. 1976 May-Jun;4(3):269-75.
8
[Biochemical studies with oxitropium bromide. 1. Pharmacokinetics and metabolism in the rat and dog].[溴化氧托品的生化研究。1. 大鼠和犬体内的药代动力学与代谢]
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9
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Arzneimittelforschung. 1966 Oct;16(10):1354-7.
10
A comparison of some of the pharmacological properties of etintidine, a new histamine H2-receptor antagonist, with those of cimetidine, ranitidine and tiotidine.新型组胺H2受体拮抗剂乙溴替丁与西咪替丁、雷尼替丁和替奥替丁某些药理特性的比较。
J Pharmacol Exp Ther. 1983 Jan;224(1):171-9.

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Examination of Urinary Excretion of Unchanged Drug in Humans and Preclinical Animal Models: Increasing the Predictability of Poor Metabolism in Humans.人体和临床前动物模型中未变化药物的尿排泄检查：提高人类代谢不良的预测性。
Pharm Res. 2021 Jul;38(7):1139-1156. doi: 10.1007/s11095-021-03076-y. Epub 2021 Jul 12.
2
Effect of acute renal failure on neurotoxicity of cimetidine in rats.急性肾衰竭对大鼠西咪替丁神经毒性的影响。
Pharm Res. 1995 Dec;12(12):1953-7. doi: 10.1023/a:1016200208174.
3
Pharmacokinetics and bioavailability of cimetidine in gastric and duodenal ulcer patients.
西咪替丁在胃溃疡和十二指肠溃疡患者中的药代动力学及生物利用度
Clin Pharmacokinet. 1980 Jan-Feb;5(1):84-94. doi: 10.2165/00003088-198005010-00003.
4
The effect of metoclopramide and propantheline on the gastrointestinal absorption of cimetidine.胃复安和丙胺太林对西咪替丁胃肠道吸收的影响。
Br J Clin Pharmacol. 1981 Jun;11(6):629-31. doi: 10.1111/j.1365-2125.1981.tb01184.x.
5
Influence of phenobarbital treatment on cimetidine kinetics.苯巴比妥治疗对西咪替丁动力学的影响。
Eur J Clin Pharmacol. 1981;19(5):343-7. doi: 10.1007/BF00544584.
6
The pharmacokinetics of cimetidine and its sulphoxide metabolite in patients with normal and impaired renal function.西咪替丁及其亚砜代谢产物在肾功能正常和受损患者中的药代动力学。
Br J Clin Pharmacol. 1982 Feb;13(2):163-70. doi: 10.1111/j.1365-2125.1982.tb01351.x.
7
Pharmacokinetics of cimetidine and its sulphoxide metabolite during haemodialysis.西咪替丁及其亚砜代谢物在血液透析期间的药代动力学。
Eur J Clin Pharmacol. 1982;21(4):325-30. doi: 10.1007/BF00637621.
8
Drug interactions with cimetidine.西咪替丁的药物相互作用。
Clin Pharmacokinet. 1982 Jan-Feb;7(1):23-41. doi: 10.2165/00003088-198207010-00002.
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The bioavailability and pharmacokinetics of cimetidine and its metabolites in juvenile cystic fibrosis patients: age related differences as compared to adults.西咪替丁及其代谢产物在青少年囊性纤维化患者中的生物利用度和药代动力学：与成人相比的年龄相关差异。
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10
Cimetidine disposition in patients with Laennec's cirrhosis during multiple dosing therapy.
Eur J Clin Pharmacol. 1983;25(2):223-9. doi: 10.1007/BF00543795.