Research Unit, Institut d'Assistència Sanitària, Girona, Spain.
Int J Neurosci. 2013 May;123(5):339-46. doi: 10.3109/00207454.2012.761216. Epub 2013 Feb 4.
Pain prevalence is high among elderly people, and equally prevalent in those with dementia. The aim of this study was to describe the use analgesics, as well as the cost of these treatments in old people with dementia.
We used a cross-sectional design using 1186 cases registered by the Registry of Dementias of Girona from 2007 to 2008. All drugs were categorized following the Anatomic Therapeutic Chemical classification and grouped according to the World Health Organization (WHO) analgesic ladder steps. Descriptive statistical methods were used.
Analgesics were prescribed to 78.6% (95% CI, 76.2-81.0) of the registered cases. Of them, 80.6% (95% CI, 78.0-83.2) were treated following step 1 of the WHO analgesic ladder, 16.8% (95% CI, 14.4-19.3) following step 2 and 2.6% (95% CI, 1.5-3.6) following step 3. Pain treatment in old people with dementia had a cost of 42.1 € per patient and year, with no significant differences depending on the subtype of dementia.
The use of analgesics in our sample was not associated to age or to dementia severity, which are themselves risk factors for increased pain. Moreover, no differences were detected depending on the subtype of dementia.
老年人疼痛的患病率很高，痴呆症患者同样如此。本研究旨在描述痴呆老年人使用镇痛药的情况，以及这些治疗的费用。
我们使用了 2007 年至 2008 年吉罗纳痴呆登记处登记的 1186 例的横断面设计。所有药物均按照解剖治疗化学分类进行分类，并根据世界卫生组织（WHO）的镇痛阶梯步骤进行分组。采用描述性统计方法。
注册病例中有 78.6%（95%CI，76.2-81.0）使用了镇痛药。其中，80.6%（95%CI，78.0-83.2）按照 WHO 镇痛阶梯的第 1 步治疗，16.8%（95%CI，14.4-19.3）按照第 2 步治疗，2.6%（95%CI，1.5-3.6）按照第 3 步治疗。痴呆老年人的疼痛治疗费用为每位患者每年 42.1 欧元，与痴呆症亚型无关，无显著差异。
我们的样本中镇痛药的使用与年龄或痴呆严重程度无关，而年龄或痴呆严重程度本身就是疼痛加剧的危险因素。此外，根据痴呆症的亚型，没有发现差异。
