Somer L, Vukadinović S, Somer T, Mikić Z, Milankov M
Acta Chir Iugosl. 1990;37 Suppl 1:51-5.
Lesions of the anterior cruciate ligament of the knee are very frequent misfortune and the results of their suture being insufficient yet, made us to explore the possibility to replace the damaged ligament with the fascia lata as an autologous transplant. Surgical operation was performed on dogs. Instead of the anterior cruciate ligament removed, we used a piece of a rolled fascia lata. Six months after transplantation being performed, samples of the fascia lata were extracted for histological analysis to assess their structure and to evaluate the transplant as a neoligament, on the basis of its similarity with the normal structure of the ligament. After degeneration of a part of transplant because of the insufficient supply of nutrients, the invasion of the synovial blood vessels into the fascia lata was established and the young granulation tissue formed on the account of the nondifferentiated adventitial cells. In the mosaic of the transplant structure there were present parts of a more mature, dense connective tissue with longitudinal orientation of the cells, the fibers and the vascular elements, which partially made structure similar to that in ligaments. In the attachment region fibrocartilage was noticed, gradually passing into the hyaline one, to merge with the hyaline cartilage of the joint surface. After the histological analysis follows the conclusion that fascia lata functionally could replace the anterior cruciate ligament if a role was supplied with sufficient collagenic fibers on the cross-section. Time is of a high importance, too.(ABSTRACT TRUNCATED AT 250 WORDS)
膝关节前交叉韧带损伤十分常见,而对其进行缝合的效果仍不尽人意,这促使我们探索用阔筋膜作为自体移植物替代受损韧带的可能性。我们在狗身上进行了手术。我们用一片卷起的阔筋膜替代被切除的前交叉韧带。在进行移植六个月后,提取阔筋膜样本进行组织学分析,以评估其结构,并根据其与韧带正常结构的相似性来评价该移植物作为新韧带的情况。由于营养供应不足,移植物的一部分发生退变后,滑膜血管侵入阔筋膜,未分化的外膜细胞形成了年轻的肉芽组织。在移植物结构的镶嵌体中,存在部分更成熟、致密的结缔组织,其细胞、纤维和血管成分呈纵向排列,这部分结构与韧带中的结构相似。在附着区域发现了纤维软骨,它逐渐过渡为透明软骨,与关节面的透明软骨融合。经过组织学分析得出结论:如果阔筋膜横截面上有足够的胶原纤维,那么在功能上它可以替代前交叉韧带。时间也非常重要。(摘要截断于250字)