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美洲鸵鸟的噻芬太尼-右美托咪定-替来他明麻醉

Thiafentanil-dexmedetomidine-telazol anesthesia in greater rheas (Rhea americana).

作者信息

Ter Beest Julia, McClean Modesto, Cushing Andrew, Bildfell Robert

机构信息

Oregon State University, College of Veterinary Medicine, Corvallis, 97331, USA.

出版信息

J Zoo Wildl Med. 2012 Dec;43(4):802-7. doi: 10.1638/2011-0175R2.1.

Abstract

Ratite anesthetic events are often dangerous because these birds use their powerful legs and clawed feet as a defense, and physical restraint can result in self-trauma or injury to handlers. Although various combinations of opioids, alpha-2 adrenergic agonists, and dissociative agents have been employed in ratites, few effective chemical immobilization protocols have been documented for rheas (Rhea spp.). An intramuscular, remote-delivered combination of thiafentanil (0.30 +/- 0.08 mg/kg), dexmedetomidine (7.31 +/- 2.72 microg/kg), and tiletamine-zolazepam (5.09 +/- 2.31 mg/kg) was utilized in eight adult (four male, four female) greater rheas (Rhea americana). Smooth inductions were observed. During clinical procedures, birds were intubated and maintained on isoflurane gas, and atipamezole was administered to antagonize the dexmedetomidine. At recovery, naltrexone was administered to antagonize the thiafentanil, and midazolam was administered to smooth crate recoveries until release. This low-volume, high-potency, reversible drug combination demonstrated safe inductions and smooth recoveries and proved to be a reliable anesthetic regimen for greater rheas.

摘要

平胸鸟类的麻醉过程往往很危险,因为这些鸟类会用它们有力的双腿和带爪的脚进行防御,身体束缚可能会导致自我创伤或对操作人员造成伤害。尽管已经在平胸鸟类中使用了阿片类药物、α-2肾上腺素能激动剂和解离剂的各种组合,但关于美洲鸵鸟(美洲鸵鸟属)的有效化学保定方案的记录却很少。在8只成年(4只雄性,4只雌性)大美洲鸵(美洲鸵鸟)中使用了经远程注射的肌内注射用噻芬太尼(0.30±0.08毫克/千克)、右美托咪定(7.31±2.72微克/千克)和替来他明-唑拉西泮(5.09±2.31毫克/千克)的组合。观察到诱导过程平稳。在临床操作过程中,对鸟类进行插管并维持异氟烷气体麻醉,同时给予阿替美唑以拮抗右美托咪定。恢复时,给予纳曲酮以拮抗噻芬太尼,并给予咪达唑仑以使笼内恢复平稳直至放归。这种小剂量、高效、可逆的药物组合显示出安全的诱导和平稳的恢复,被证明是大美洲鸵可靠的麻醉方案。

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