School of Public Health, China Medical University, Shenyang, China.
J Photochem Photobiol B. 2013 Mar 5;120:163-70. doi: 10.1016/j.jphotobiol.2012.11.010. Epub 2012 Dec 7.
To determine the extent of and the contributing factors in skin ageing in the Chinese population, we collected data on 691 participants in northern (high latitude region) and southern China (low latitude region). The skin damage of the participants was graded according to a Beagley-Gibson scoring system based on photographs of the dorsal hand skin. The results revealed that age was an important contributing factor for skin damage. In both regions, the mean skin damage grade increased with age. The mean skin damage grade for the subjects in the low latitude region was significantly higher than that for those in the high latitude region in all of the age groups (P<0.05). There was nearly a 10-year delay before the high latitude region subjects achieved the same degree of hand skin damage as the low latitude region subjects. Lifetime sun exposure was another independent factor that influenced the degree of skin damage. As age increased, the difference in the lifetime sun exposure between the two regions increased, but the difference in the extent of skin damage decreased. Skin damage on the hand may be more affected by sun exposure early in life. Furthermore, female sex and a higher body mass index (i.e., ⩾24.0) were associated with a lower skin damage grade (adjusted odds ratio [AOR] 0.54, 95% CI 0.40-0.73 and AOR 0.40, 95% CI 0.25-0.65, respectively). Compared with the subjects who lived at high latitude, those who lived at low latitude had an increased risk of a higher score (5.22; 95% CI, 3.68-7.42).
为了确定中国人皮肤老化的程度和影响因素，我们收集了来自中国北方（高纬度地区）和南方（低纬度地区）的 691 名参与者的数据。根据手部背部皮肤照片的 Beagley-Gibson 评分系统对参与者的皮肤损伤进行分级。结果表明，年龄是皮肤损伤的一个重要影响因素。在两个地区，平均皮肤损伤等级随年龄增长而增加。在所有年龄组中，低纬度地区的受试者的平均皮肤损伤等级均显著高于高纬度地区的受试者（P<0.05）。高纬度地区的受试者需要近 10 年的时间才能达到与低纬度地区受试者相同程度的手部皮肤损伤。终生阳光暴露是另一个影响皮肤损伤程度的独立因素。随着年龄的增长，两个地区之间的终生阳光暴露差异增大，但皮肤损伤程度的差异减小。手部皮肤损伤可能更多地受到早年阳光暴露的影响。此外，女性和较高的身体质量指数（即 ⩾24.0）与较低的皮肤损伤等级相关（调整后的比值比 [AOR] 0.54，95%置信区间 [CI] 0.40-0.73 和 AOR 0.40，95%CI 0.25-0.65）。与生活在高纬度地区的受试者相比，生活在低纬度地区的受试者出现较高评分的风险增加（5.22；95%CI，3.68-7.42）。
