Bak Mihály, Hidvégi Judit, Andi Judit, Bahéry Mária, Kovács Eszter, Schneider Ferenc, Kostic Szilárd, Rényi-Vámos Ferenc, Szőke János, Nyári Tibor, Gődény Mária, Kásler Miklós
Országos Onkológiai Intézet Budapest.
Orv Hetil. 2013 Jan 6;154(1):28-32. doi: 10.1556/OH.2013.29519.
The methods available for the diagnosis of lung cancer include radiologic, cytologic and pathologic procedures.
The aim of this study was to determine the quality assurance of CT guided fine needle aspiration cytology of lung nodules.
Cytology results were rated to 4 categories (positive; suspicious; negative; not representative). All cytology reports were compared with the final histology diagnosis.
A total of 128 patients underwent CT-guided percutaneous fine-needle aspiration biopsy cytology (63 males; 65 females; mean age 62.8 years). Smears were adequate in 99 cases and inadequate in 29 cases. The average diameter of the nodules was 3.28 cm. Thirty three (25.6%) of the cases were histologically verified and 2 falsely negative and 2 falsely positive cases were detected. The sensitivity and the positive predictive value were 88.8% and 88.8%, respectively. Pneumothorax developed in 7 (5.4%) cases.
These results suggest that CT-guided transthoracic fine needle aspiration cytology has a high diagnostic accuracy and an acceptable complication rate. The auditing valves of the results meet the proposed threshold values.
可用于肺癌诊断的方法包括放射学、细胞学和病理学检查程序。
本研究的目的是确定CT引导下肺结节细针穿刺细胞学检查的质量保证。
细胞学结果分为4类（阳性；可疑；阴性；无代表性）。所有细胞学报告均与最终组织学诊断进行比较。
共有128例患者接受了CT引导下经皮细针穿刺活检细胞学检查（男性63例；女性65例；平均年龄62.8岁）。涂片质量良好的有99例，质量不佳的有29例。结节的平均直径为3.28厘米。33例（25.6%）经组织学证实，检测到2例假阴性和2例假阳性病例。敏感性和阳性预测值分别为88.8%和88.8%。7例（5.4%）发生气胸。
这些结果表明，CT引导下经胸细针穿刺细胞学检查具有较高的诊断准确性和可接受的并发症发生率。结果的审核标准符合建议的阈值。
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