Bosch Mestres J, Esque Ruiz M, Carbonell Estrany X
Laboratorio de Microbiología, Departamento de Pediatría, Casa de Maternitat, Barcelona.
An Esp Pediatr. 1990 Jan;32(1):70-2.
Three cases of serious infections due to Candida parapsilosis in infants are reported. Two patients are children exposed to abdominal surgery, parenteral nutrition and antibiotic treatment, who developed catheter-associated sepsis with successful response to change of catheter and intravenous amphotericin B, despite one of the patients showed a relapse some weeks after. Third patient, a hydrocephalic child with external ventricular shunt, developed cerebrospinal fluid infection without response to antifungal treatment and died. Sepsis and meningitis due to Candida parapsilosis can be observed in infants with some risk factors, as use of intravascular or intraventricular catheters. Change of the catheter and treatment with amphotericin B are indicated in these infections.
报告了3例婴儿因近平滑念珠菌引起的严重感染。2例患者为接受腹部手术、肠外营养和抗生素治疗的儿童，发生了导管相关败血症，更换导管并静脉注射两性霉素B后取得成功，尽管其中1例患者在数周后出现复发。第3例患者是一名患有外部脑室分流术的脑积水儿童，发生了脑脊液感染，抗真菌治疗无效并死亡。近平滑念珠菌引起的败血症和脑膜炎可在有某些危险因素的婴儿中观察到，如使用血管内或脑室内导管。这些感染需要更换导管并使用两性霉素B进行治疗。
