Prieto Bozano G, Ortega Páez E, Escribano Burgos C, Benito Bartolomé F, Herranz Macías A, Polanco Allúe I
Unidad de Gastroenterología y Nutrición, Hospital Infantil La Paz, Madrid.
An Esp Pediatr. 1990 Jan;32(1):73-5.
Two patients with protein-losing enteropathy of cardiac origin, one case due to constrictive pericarditis and another as a complication of a Fontan operation, are presented. In both cases the clinical symptomatology and the analytical pattern were very suggestive of loss of protein through the intestinal lumen. This was confirmed by the determination of fecal fecal alpha-1-antitrypsin (alpha-1-AT) and its intestinal clearance. The utility of both determinations as a simple and secure method in substitution of isotopic studies is emphasized.
本文介绍了两名心源型蛋白丢失性肠病患者，一例由缩窄性心包炎引起，另一例为Fontan手术并发症。在这两例中，临床症状和分析模式都强烈提示蛋白质通过肠腔丢失。通过测定粪便中的α-1抗胰蛋白酶（α-1-AT）及其肠道清除率得以证实。强调了这两种测定方法作为替代同位素研究的简单可靠方法的实用性。
