在社区中使用蒙特利尔认知评估量表和简易精神状态检查表对75岁及以上的极轻度皮质下血管性痴呆患者进行筛查:栗原项目
Screening for very mild subcortical vascular dementia patients aged 75 and above using the montreal cognitive assessment and mini-mental state examination in a community: the kurihara project.
作者信息
Kasai Mari, Meguro Kenichi, Nakamura Kei, Nakatsuka Masahiro, Ouchi Yoshitaka, Tanaka Naofumi
机构信息
Department of Geriatric Behavioral Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.
出版信息
Dement Geriatr Cogn Dis Extra. 2012 Jan;2(1):503-15. doi: 10.1159/000340047. Epub 2012 Nov 10.
AIMS
To examine the effectiveness of the Montreal Cognitive Assessment (MoCA) to screen people with mild cognitive impairment (MCI), to associate the MoCA score with the presence of infarction, and to detect the characteristics of people with very mild subcortical vascular dementia (vmSVD).
METHODS
392 out of 886 community dwellers aged 75 years and above living in Kurihara, Northern Japan, agreed to participate in our study; 164 scored a Clinical Dementia Rating (CDR) of 0 (healthy), 184 scored a CDR of 0.5 (MCI) and 44 scored a CDR of 1+ (dementia). The participants scoring a CDR of 0.5 were divided into 2 subtypes: 37 had vmSVD and 147 had other types of dementia. The objective variables were the total MoCA, the MoCA subscale and the Mini-Mental State Examination (MMSE).
RESULTS
There was a difference in the MoCA and MMSE scores between the 3 CDR groups. The MoCA score overlapped in participants with CDR 0 and 0.5. There were significant CDR effects, while there were no significant infarction effects for the MoCA and MMSE. vmSVD participants had lower scores on the total MoCA, the MoCA attention subscale and MMSE than healthy elderly people and participants with other types of dementia.
CONCLUSION
Our results suggested that MMSE performed rather well and that the MoCA is not superior to MMSE in MCI and vmSVD participants aged 75 and above in a community.
目的
探讨蒙特利尔认知评估量表(MoCA)筛查轻度认知障碍(MCI)患者的有效性,将MoCA评分与梗死情况相关联,并检测极轻度皮质下血管性痴呆(vmSVD)患者的特征。
方法
居住在日本北部栗原市的886名75岁及以上社区居民中,有392人同意参与我们的研究;164人临床痴呆评定量表(CDR)评分为0(健康),184人CDR评分为0.5(MCI),44人CDR评分为1+(痴呆)。CDR评分为0.5的参与者分为2个亚型:37人患有vmSVD,147人患有其他类型痴呆。客观变量为MoCA总分、MoCA子量表和简易精神状态检查表(MMSE)。
结果
3个CDR组之间的MoCA和MMSE评分存在差异。CDR评分为0和0.5的参与者的MoCA评分有重叠。存在显著的CDR效应,而MoCA和MMSE没有显著的梗死效应。vmSVD参与者的MoCA总分、MoCA注意力子量表和MMSE得分低于健康老年人和其他类型痴呆的参与者。
结论
我们的结果表明,在社区中75岁及以上的MCI和vmSVD参与者中,MMSE表现相当良好,且MoCA并不优于MMSE。
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