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澳大利亚全科医生开具阿片类药物治疗慢性非恶性疼痛的处方评估。

An evaluation of the prescription of opioids for chronic nonmalignant pain by Australian general practitioners.

机构信息

Albert St Medical Centre, Taree, Australia.

出版信息

Pain Med. 2013 Jan;14(1):62-74. doi: 10.1111/j.1526-4637.2012.01527.x. Epub 2012 Dec 28.

Abstract

OBJECTIVE

Our objective was to evaluate the quality of opioid analgesia prescribing in chronic nonmalignant pain (CNMP) by general practitioners (GPs, family physicians).

DESIGN

An anonymous, cross-sectional questionnaire-based survey.

SETTING

The setting was five Australian divisions of general practice (geographically based associations of GPs).

METHODS

A questionnaire was mailed to all division members. Outcome measures were adherence to individual recommendations of locally derived CNMP practice guidelines.

RESULTS

We received 404 responses (response rate 23.3%). In the previous fortnight, GPs prescribed long-term continuous opioids for CNMP for a median of 4 and a mean of 7.1 (±8.7) patients with CNMP. Guideline concordance (GLC) was poor, with no GP always compliant with all guideline items, and only 31% GPs usually employing most items. GLC was highest for the avoidance of high dosages or fast-acting formulations. It was lowest for strategies minimizing individual and public health harms, such as the initiation of opioids on a time-limited trial basis, use of contracts, and the preclusion or management of aberrant behaviors. GLC was positively associated with relevant training or qualifications, registration with the Australian Prescription Drug Monitoring Programme, being an opioid substitution therapy prescriber, and female gender.

CONCLUSIONS

In this study, long-term opioids were frequently initiated for CNMP without a quality use-of-medicine approach. Potential sequelae are inadequate treatment of pain and escalating opioid-related harms. These data suggest a need for improved resourcing and training in opioid management across pain and addictions.

摘要

目的

我们的目的是评估全科医生(GP,家庭医生)在慢性非恶性疼痛(CNMP)中的阿片类镇痛药处方质量。

设计

一项匿名的、基于横断面问卷的调查。

设置

该设置是五个澳大利亚普通科医生分部(以地理为基础的 GP 协会)。

方法

向所有分部成员邮寄了一份问卷。主要结果是遵守当地衍生的 CNMP 实践指南的个别建议。

结果

我们收到了 404 份回复(回复率为 23.3%)。在过去两周内,GP 为 CNMP 开具了长期连续阿片类药物,中位数为 4 例,平均为 7.1(±8.7)例 CNMP 患者。指南一致性(GLC)较差,没有 GP 始终遵守所有指南项目,只有 31%的 GP 通常使用大多数项目。对于避免高剂量或速释制剂,GLC 最高。对于最大限度减少个人和公共卫生危害的策略,如在有限的试验基础上启动阿片类药物、使用合同以及排除或管理异常行为,GLC 最低。GLC 与相关培训或资格、澳大利亚处方药物监测计划的注册、作为阿片类药物替代治疗处方者以及女性性别呈正相关。

结论

在这项研究中,长期阿片类药物经常被用于 CNMP,而没有采用质量用药方法。潜在的后果是疼痛治疗不足和阿片类药物相关危害加剧。这些数据表明,需要在疼痛和成瘾领域加强阿片类药物管理的资源和培训。

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