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用于慢性非恶性疼痛的阿片类药物。加州大学旧金山分校/斯坦福大学合作研究网络中初级保健医生的态度和实践。加利福尼亚大学旧金山分校

Opioids for chronic nonmalignant pain. Attitudes and practices of primary care physicians in the UCSF/Stanford Collaborative Research Network. University of California, San Francisco.

作者信息

Potter M, Schafer S, Gonzalez-Mendez E, Gjeltema K, Lopez A, Wu J, Pedrin R, Cozen M, Wilson R, Thom D, Croughan-Minihane M

机构信息

Department of Family and Community Medicine University of California, San Francisco 94143-0900, USA.

出版信息

J Fam Pract. 2001 Feb;50(2):145-51.

PMID:11219563
Abstract

BACKGROUND

We hoped to determine the attitudes and practices of primary care physicians regarding the use of opioids to treat chronic nonmalignant pain (CNMP). We also examined the factors associated with the willingness to prescribe opioids for CNMP.

METHODS

A survey was mailed to primary care physicians in the University of California, San Francisco/Stanford Collaborative Research Network. This survey contained questions regarding treatment in response to 3 case vignettes, the use of opioids for CNMP in general, and the demographic characteristics of the physicians.

RESULTS

Among 230 physicians surveyed, 161 (70%) responded. Two percent of the respondents were never willing to prescribe schedule III opioids (eg, acetaminophen with codeine) as needed for patients with CNMP that persisted unchanged after exhaustive evaluation and attempts at treatment. Thirty-five percent were never willing to prescribe schedule II opioids (eg, sustained-release morphine) on an around-the-clock schedule for these patients. The most significant predictor of willingness to prescribe opioids for patients with CNMP was a lower level of concern about physical dependence, tolerance, and addiction.

CONCLUSIONS

Primary care physicians are willing to prescribe schedule III opioids as needed, but many are unwilling to use schedule II opioids around the clock for CNMP. Individual prescribing practices vary widely among primary care physicians. Concerns about physical dependence, tolerance, and addiction are barriers to the prescription of opioids by primary care physicians for patients with CNMP.

摘要

背景

我们希望确定基层医疗医生在使用阿片类药物治疗慢性非恶性疼痛(CNMP)方面的态度和做法。我们还研究了与愿意为CNMP开具阿片类药物相关的因素。

方法

向加利福尼亚大学旧金山分校/斯坦福合作研究网络中的基层医疗医生邮寄了一份调查问卷。该调查问卷包含针对3个病例 vignettes 的治疗问题、阿片类药物在CNMP中的一般使用情况以及医生的人口统计学特征。

结果

在接受调查的230名医生中,161名(70%)做出了回应。2%的受访者从不愿意根据需要为经过详尽评估和治疗尝试后病情未改善的CNMP患者开具III类阿片(如对乙酰氨基酚可待因)。35%的受访者从不愿意为这些患者全天候开具II类阿片(如缓释吗啡)。为CNMP患者开具阿片类药物意愿的最显著预测因素是对身体依赖、耐受性和成瘾性的担忧程度较低。

结论

基层医疗医生愿意根据需要开具III类阿片,但许多人不愿意为CNMP患者全天候使用II类阿片。基层医疗医生的个人处方做法差异很大。对身体依赖、耐受性和成瘾性的担忧是基层医疗医生为CNMP患者开具阿片类药物的障碍。

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