Department of Psychiatry, Abant Izzet Baysal University, Bolu, Turkey.
Eur Rev Med Pharmacol Sci. 2012 Dec;16(15):2108-12.
Paroxysmal supraventricular tachycardia (PSVT) has been shown to be associated with poor outcome in psychological status and quality of life. This study aimed to assess the quality-of-life and anxiety in patients with PSVT and to investigate the influence of radiofrequency ablation (RFA) treatment on these parameters.
Fifty patients with newly diagnosed PSVT with electrophysiologic study and treated with RFA, were enrolled in the study and 50 healthy age-and sex-matched individuals. The brief version of World Health Organization Quality of Life Scale and the state-trait anxiety inventory were administered to controls and all patients before and three months after the RFA procedure.
At baseline, in comparison with the control group, the patients with PSVT exhibited greater anxiety average scores (p < 0.05). After RFA procedure, the patients with PSVT exhibited significant improvement in anxiety, quality of life and health satisfaction scores. Statistically significant difference between the controls and the patients in respect to state and trait anxiety average scores disappeared after treatment (p > 0.05).
In this study, normalization of anxiety and quality of life is associated with RFA treatment for patients with PSVT. This finding need to be confirmed by larger scale clinical trials with long-term quality of life follow-up in higher number of patients.
阵发性室上性心动过速(PSVT)与心理状态和生活质量较差有关。本研究旨在评估 PSVT 患者的生活质量和焦虑,并探讨射频消融(RFA)治疗对这些参数的影响。
本研究纳入了 50 例新诊断的 PSVT 患者,这些患者进行了电生理研究并接受了 RFA 治疗,同时纳入了 50 名年龄和性别相匹配的健康对照者。在 RFA 术前和术后 3 个月,为对照组和所有患者使用世界卫生组织生活质量量表简短版和状态-特质焦虑量表进行评估。
与对照组相比,PSVT 患者在基线时的平均焦虑评分更高(p<0.05)。在 RFA 术后,PSVT 患者的焦虑、生活质量和健康满意度评分显著改善。治疗后,对照组和患者之间的状态和特质焦虑平均评分之间的统计学差异消失(p>0.05)。
在这项研究中,RFA 治疗与 PSVT 患者的焦虑和生活质量正常化相关。这一发现需要通过更大规模的临床试验,对更多患者进行长期生活质量随访来进一步证实。