Department of Ophthalmology, Blekinge Hospital, Karlskrona, SwedenDepartment of Ophthalmology, Sahlgrenska Academy, University of Gothenburg, Mölndal, SwedenDepartment of Clinical Sciences, Ophthalmology, Faculty of Medicine, Lund University, Lund, Sweden.
Acta Ophthalmol. 2014 Mar;92(2):179-83. doi: 10.1111/aos.12026. Epub 2012 Dec 31.
To evaluate the posterior capsule opacification (PCO) rates in three different modern standard intraocular lenses (IOL) and analyse the related cost.
Retrospective study of medical records from 1527 patients who underwent uneventful cataract surgery by phacoemulsification with posterior chamber implantation of either AcrySof SN60 (n = 375), Akreos Adapt (n = 350) or Tecnis Acryl IOL (n = 801). All surgeries were performed by the same surgeon using the same surgical technique and equipment. Primary end-point was neodymium:yttrium-aluminium-garnet (Nd:YAG) capsulotomy for visual impairment secondary to PCO. Cost of IOL material and Nd:YAG capsulotomy for PCO was then evaluated and compared between the IOLs.
Mean follow-up was 41.5 months, and the only statistically significant variable of developing PCO was IOL type and individual follow-up time. Nd:YAG capsulotomy was performed in 7.47% in the AcrySof group, 17.71% in the Akreos group and 3.75% in the Tecnis group. Average cost for Nd:YAG capsulotomy per surgery was €18.75 in the AcrySof SN60 group, €44.25 in the Akreos Adapt group and €9.25 in the Tecnis Acryl group. The combined cost of cataract surgery and PCO treatment was €9.81 higher in for the Akreos Adapt group than the other two combined.
This retrospective study shows that the risk of PCO and Nd:YAG capsulotomy is significantly higher in hydrophilic Akreos IOL compared with both AcrySof and Tecnis hydrophobic IOLs. The increased risk of PCO in the hydrophilic IOL is related to higher total average costs for cataract surgery.
评估三种不同现代标准人工晶状体(IOL)的后囊混浊(PCO)发生率,并分析相关成本。
回顾性分析 1527 例接受超声乳化白内障吸除术并植入后房型人工晶状体的患者的病历资料,其中 AcrySof SN60 组(n = 375)、Akreos Adapt 组(n = 350)和 Tecnis Acryl IOL 组(n = 801)。所有手术均由同一位医生使用相同的手术技术和设备完成。主要终点是因 PCO 导致视觉损害而进行钕:钇铝石榴石(Nd:YAG)后囊切开术。然后评估和比较三种 IOL 的 IOL 材料和 Nd:YAG 后囊切开术治疗 PCO 的成本。
平均随访时间为 41.5 个月,发生 PCO 的唯一具有统计学意义的变量是 IOL 类型和个体随访时间。AcrySof 组、Akreos 组和 Tecnis 组分别有 7.47%、17.71%和 3.75%的患者行 Nd:YAG 后囊切开术。AcrySof SN60 组每例手术 Nd:YAG 后囊切开术的平均费用为 18.75 欧元,Akreos Adapt 组为 44.25 欧元,Tecnis Acryl 组为 9.25 欧元。与其他两组相比,Akreos Adapt 组的白内障手术和 PCO 治疗的综合成本增加了 9.81 欧元。
这项回顾性研究表明,与 AcrySof 和 Tecnis 疏水性 IOL 相比,亲水性 Akreos IOL 发生 PCO 和 Nd:YAG 后囊切开术的风险显著更高。亲水性 IOL 发生 PCO 的风险增加与白内障手术的总平均成本较高有关。