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[老年内科住院患者的谵妄:一项为期一年的随访研究]

[Delirium in older medical inpatients: a one year follow up study].

作者信息

Carrasco Marcela, Accatino-Scagliotti Luigi, Calderón Jorge, Villarroel Luis, Marín Pedro Paulo, González Matías

机构信息

Programa de Geriatría, Departamento de Medicina Interna, Pontificia Universidad Católica de Chile, Santiago, Chile.

出版信息

Rev Med Chil. 2012 Jul;140(7):847-52. doi: 10.4067/S0034-98872012000700003.

Abstract

BACKGROUND

Delirium is an important problem in older medical inpatients.

AIM

To assess if delirium is associated with higher mortality, functional decline or higher rates of readmission or institutionalization in a one year follow-up period.

MATERIAL AND METHODS

Prospective cohort study of consecutive patients 65 years and older, admitted to a general hospital medical ward. A psychogeriatric team assessed patients every 48 h using the Confusion Assessment Method (CAM), functionality, acute severity and comorbidity scores. Analysis of one year mortality and telephone functional assessment was performed.

RESULTS

Five hundred forty two patients were enrolled and 35.4% had delirium. After one year, mortality was 34.9 and 13% in delirium and non-delirium cohorts, respectively (p < 0.01). After adjustment for covariates, delirium was independently associated with higher mortality, and higher functional decline and institutionalization. No significant differences were seen in readmission rates.

CONCLUSIONS

Delirium was significantly associated with higher mortality and functional decline over a one year follow up period in geriatric inpatients.

摘要

背景

谵妄是老年内科住院患者的一个重要问题。

目的

评估在一年的随访期内,谵妄是否与更高的死亡率、功能衰退、再入院率或机构化率相关。

材料与方法

对一家综合医院内科病房收治的65岁及以上连续患者进行前瞻性队列研究。一个老年精神科团队每48小时使用谵妄评估方法(CAM)、功能、急性严重程度和共病评分对患者进行评估。进行了一年死亡率分析和电话功能评估。

结果

共纳入542例患者,35.4%的患者发生谵妄。一年后,谵妄组和非谵妄组的死亡率分别为34.9%和13%(p<0.01)。在对协变量进行调整后,谵妄与更高的死亡率、更高的功能衰退和机构化独立相关。再入院率未见显著差异。

结论

在老年住院患者一年的随访期内,谵妄与更高的死亡率和功能衰退显著相关。

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