Cicero Mark X, Cross Keith P
Department of Pediatrics, Yale-New Haven Hospital, Yale School of Medicine, New Haven, CT 06511, USA.
Pediatr Emerg Care. 2013 Jan;29(1):43-8. doi: 10.1097/PEC.0b013e31827b52bf.
The objective of this study was to determine the predictive value of the Glasgow coma scale (GCS) and the Glasgow motor component (GMC) for overall mortality, death on arrival, and major injury and the relationship between GCS and length of stay (LOS) in the emergency department (ED) and hospital.
Records from the American College of Surgeons National Trauma Data Base from 2007 to 2009 were extracted. Patients 0 to 18 years old transported from a trauma scene with complete initial scene data were included. Statistical analysis, including construction of receiver-operator curves, determined the correlation between GCS, GMC, and the clinical outcomes of interest.
There were 104,035 records with complete data for analysis, including 3946 deaths. Mean patient age was 12.6 (SD, 5.5) years. Glasgow coma scale was predictive of overall mortality, with area under the receiver-operator curve (AUC) of 0.946 (95% confidence interval [CI], 0.941-0.951); death on arrival, with AUC of 0.958 (95% CI, 0.953-0.963); and risk of major injury, with AUC of 0.720 (0.715-0.724). Lower GCS scores were associated with shorter ED LOS and longer hospital stays (P <0.001, analysis of variance) except GCS 3, associated with shorter hospitalizations. For predicting overall mortality, the AUC for GMC was 0.940 (95% CI, 0.935-0.945), and for predicting major injury, the AUC was 0.681 (95% CI, 0.677-0.686).
For pediatric trauma victims, the GCS is predictive of mortality and injury outcomes, as well as both ED and hospital LOS, and has excellent prognostic accuracy. The GMC has predictive value for injury and mortality that is nearly equivalent to the full GCS.
本研究的目的是确定格拉斯哥昏迷量表(GCS)和格拉斯哥运动评分(GMC)对总体死亡率、入院时死亡、严重损伤的预测价值,以及GCS与急诊科(ED)和医院住院时间(LOS)之间的关系。
提取2007年至2009年美国外科医师学会国家创伤数据库的记录。纳入从创伤现场转运的0至18岁且初始现场数据完整的患者。包括绘制受试者工作特征曲线在内的统计分析确定了GCS、GMC与感兴趣的临床结局之间的相关性。
有104,035条记录具有完整数据用于分析,包括3946例死亡。患者平均年龄为12.6(标准差,5.5)岁。格拉斯哥昏迷量表可预测总体死亡率,受试者工作特征曲线下面积(AUC)为0.946(95%置信区间[CI],0.941 - 0.951);入院时死亡,AUC为0.958(95%CI,0.953 - 0.963);严重损伤风险,AUC为0.720(0.715 - 0.724)。较低的GCS评分与较短的急诊科住院时间和较长的医院住院时间相关(P<0.001,方差分析),但GCS 3分与较短的住院时间相关。对于预测总体死亡率,GMC的AUC为0.940(95%CI,0.935 - 0.945),对于预测严重损伤,AUC为0.681(95%CI,0.677 - 0.686)。
对于儿童创伤受害者,GCS可预测死亡率和损伤结局,以及急诊科和医院的住院时间,且具有出色的预后准确性。GMC对损伤和死亡率的预测价值几乎等同于完整的GCS。