From the *Department of Dermatology and Allergy, Biederstein, Technische Universität München (TUM), Munich; and †Division of Environmental Dermatology and Allergy GSF/TUM, GSF National Research Center for Environment and Health, Neuherberg, Germany.
World Allergy Organ J. 2008 Mar;1(3):47-50. doi: 10.1097/WOX.0b013e318165b9c1.
Specific immunotherapy (SIT) protocols for nutritional allergens have only recently been established with a focus on oral allergy syndrome because of pollen cross-reacting antibodies. For these patients, a substantial number of studies have been published suggesting benefits from SIT. The situation in true anaphylaxis to food allergens such as peanut allergy is more complex, and therapeutic strategies are based on individual protocols rather than controlled studies. However, in defined cases, SIT represents a promising approach for a durable protection from life-threatening risks after accidental ingestion.
针对营养性过敏原的特异性免疫疗法(SIT)方案最近才刚刚建立,其重点是花粉交叉反应性抗体引起的口腔过敏综合征。对于这些患者,已经发表了大量研究表明 SIT 有益。真正的食物过敏原过敏(如花生过敏)的情况更为复杂,治疗策略基于个体化方案而非对照研究。然而,在明确的情况下,SIT 代表了一种有前途的方法,可以在意外摄入后提供持久的、避免危及生命的风险的保护。