• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

（2-（苯并[d]噻唑-2-基甲氧基）-5-氯苯基）（苯基）甲酮

(2-(Benzo[d]thia-zol-2yl-meth-oxy)-5-chloro-phen-yl)(phen-yl)methanone.

作者信息

Venugopala K N, Nayak Susanta K, Govender Thavendran, Kruger Hendrik G, Maguire Glenn E M

机构信息

School of Pharmacy and Pharmacology, University of KwaZulu-Natal, Durban 4000, South Africa.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3125. doi: 10.1107/S1600536812041888. Epub 2012 Oct 13.

DOI:10.1107/S1600536812041888
PMID:23284450
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3515230/
Abstract

In the title compound, C(21)H(14)ClNO(2)S, the dihedral angle between the benzothia-zole and diphenyl methanone groups is 68.6 (2)°. The crystal structure consists of dimeric units generated by C-H⋯N bonds, further linked by C-H⋯O bonds and C-H⋯π and π-π inter-actions [centroid-centroiddistance = 3.856 (2) Å], which lead to a criss-cross assembly parallel to (001).

摘要

在标题化合物C₂₁H₁₄ClNO₂S中，苯并噻唑基团与二苯甲酮基团之间的二面角为68.6（2）°。晶体结构由通过C—H⋯N键形成的二聚体单元组成，这些单元通过C—H⋯O键以及C—H⋯π和π-π相互作用[质心-质心距离 = 3.856（2）Å]进一步连接，从而导致形成平行于（001）的交叉堆积结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1af2/3515230/b9f0135f3940/e-68-o3125-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1af2/3515230/580849f5c965/e-68-o3125-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1af2/3515230/b9f0135f3940/e-68-o3125-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1af2/3515230/580849f5c965/e-68-o3125-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1af2/3515230/b9f0135f3940/e-68-o3125-fig2.jpg

相似文献

1
(2-(Benzo[d]thia-zol-2yl-meth-oxy)-5-chloro-phen-yl)(phen-yl)methanone.（2-（苯并[d]噻唑-2-基甲氧基）-5-氯苯基）（苯基）甲酮
Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3125. doi: 10.1107/S1600536812041888. Epub 2012 Oct 13.
2
{2-[(1,3-Benzo-thia-zol-2-yl)meth-oxy]-5-chloro-phen-yl}(4-chloro-phen-yl)methan-one.{2 - [(1,3 - 苯并噻唑 - 2 - 基)甲氧基] - 5 - 氯苯基}(4 - 氯苯基)甲酮
Acta Crystallogr Sect E Struct Rep Online. 2013 Jun 19;69(Pt 7):o1124. doi: 10.1107/S1600536813016243. eCollection 2013.
3
{2-[(1,3-Benzo-thia-zol-2-yl)meth-oxy]-5-bromo-phen-yl}(phen-yl)methanone.{2 - [(1,3 - 苯并噻唑 - 2 - 基)甲氧基] - 5 - 溴苯基}(苯基)甲酮
Acta Crystallogr Sect E Struct Rep Online. 2013 May 31;69(Pt 6):o984. doi: 10.1107/S1600536813014086. Print 2013 Jun 1.
4
{2-[(1,3-Benzo-thia-zol-2-yl)meth-oxy]-5-fluoro-phen-yl}(4-chloro-phen-yl)methanone.{2 - [(1,3 - 苯并噻唑 - 2 - 基)甲氧基] - 5 - 氟苯基}(4 - 氯苯基)甲酮
Acta Crystallogr Sect E Struct Rep Online. 2013 Jun 8;69(Pt 7):o1007-8. doi: 10.1107/S1600536813014621. eCollection 2013.
5
[2-(1,3-Benzothia-zol-2-ylmeth-oxy)-5-bromo-phen-yl](4-chloro-phen-yl)methanone.[2-(1,3-苯并噻唑-2-基甲氧基)-5-溴苯基](4-氯苯基)甲酮
Acta Crystallogr Sect E Struct Rep Online. 2013 Jan 1;69(Pt 1):o70. doi: 10.1107/S1600536812049756. Epub 2012 Dec 12.
6
[4-(4-Meth-oxy-phen-yl)-2-(pyridin-3-yl)-1,3-thia-zol-5-yl][4-(tri-fluoro-meth-yl)phen-yl]methanone.[4-(4-甲氧基苯基)-2-(吡啶-3-基)-1,3-噻唑-5-基][4-(三氟甲基)苯基]甲酮
Acta Crystallogr Sect E Struct Rep Online. 2013 Aug 17;69(Pt 9):o1434. doi: 10.1107/S1600536813021259. eCollection 2013.
7
2-(5-Chloro-1,3-benzothia-zol-2-yl)-4-meth-oxy-phenol.2-（5-氯-1,3-苯并噻唑-2-基）-4-甲氧基苯酚
Acta Crystallogr Sect E Struct Rep Online. 2012 Oct 1;68(Pt 10):o2877. doi: 10.1107/S1600536812037804. Epub 2012 Sep 8.
8
4-{2-[5-(4-Chloro-phen-yl)-1-(4-fluoro-phen-yl)-1H-pyrazol-3-yl]thia-zol-4-yl}benzonitrile.4-{2-[5-(4-氯苯基)-1-(4-氟苯基)-1H-吡唑-3-基]噻唑-4-基}苯甲腈
Acta Crystallogr Sect E Struct Rep Online. 2010 Aug 11;66(Pt 9):o2286-7. doi: 10.1107/S1600536810031405.
9
2-[6-(4-Chloro-phen-yl)imidazo[2,1-b][1,3]thia-zol-2-yl]-N'-[(E)-4-meth-oxy-benzyl-idene]acetohydrazide.2-[6-(4-氯苯基)咪唑并[2,1-b][1,3]噻唑-2-基]-N'-[(E)-4-甲氧基亚苄基]乙酰肼
Acta Crystallogr Sect E Struct Rep Online. 2010 Dec 18;67(Pt 1):o184-5. doi: 10.1107/S1600536810052359.
10
1-(4-Chloro-phen-yl)-2-[4-hy-droxy-3-(3-meth-oxy-benzo-yl)-1,1-dioxo-2H-1λ(6),2-benzothia-zin-2-yl]ethanone.1-（4-氯苯基）-2-[4-羟基-3-（3-甲氧基苯甲酰基）-1,1-二氧代-2H-1λ(6),2-苯并噻嗪-2-基]乙酮
Acta Crystallogr Sect E Struct Rep Online. 2012 Apr 1;68(Pt 4):o1058-9. doi: 10.1107/S160053681201029X. Epub 2012 Mar 14.

引用本文的文献

1
{2-[(1,3-Benzo-thia-zol-2-yl)meth-oxy]-5-chloro-phen-yl}(4-chloro-phen-yl)methan-one.{2 - [(1,3 - 苯并噻唑 - 2 - 基)甲氧基] - 5 - 氯苯基}(4 - 氯苯基)甲酮
Acta Crystallogr Sect E Struct Rep Online. 2013 Jun 19;69(Pt 7):o1124. doi: 10.1107/S1600536813016243. eCollection 2013.
2
{2-[(1,3-Benzo-thia-zol-2-yl)meth-oxy]-5-fluoro-phen-yl}(4-chloro-phen-yl)methanone.{2 - [(1,3 - 苯并噻唑 - 2 - 基)甲氧基] - 5 - 氟苯基}(4 - 氯苯基)甲酮
Acta Crystallogr Sect E Struct Rep Online. 2013 Jun 8;69(Pt 7):o1007-8. doi: 10.1107/S1600536813014621. eCollection 2013.
3
[2-(1,3-Benzothia-zol-2-ylmeth-oxy)-5-bromo-phen-yl](4-chloro-phen-yl)methanone.

本文引用的文献

1
Novel 2-(2-(4-aryloxybenzylidene) hydrazinyl)benzothiazole derivatives as anti-tubercular agents.新型 2-(2-(4-芳氧基苯亚甲基)腙基)苯并噻唑衍生物作为抗结核药物。
Bioorg Med Chem Lett. 2012 Jan 1;22(1):649-52. doi: 10.1016/j.bmcl.2011.10.064. Epub 2011 Oct 30.
2
Synthesis, characterization and biological evaluation of some thiourea derivatives bearing benzothiazole moiety as potential antimicrobial and anticancer agents.合成、表征及含苯并噻唑基的硫脲衍生物的生物评价作为潜在的抗菌和抗癌药物。
Eur J Med Chem. 2010 Apr;45(4):1323-31. doi: 10.1016/j.ejmech.2009.12.016. Epub 2009 Dec 16.
3
Structure validation in chemical crystallography.
[2-(1,3-苯并噻唑-2-基甲氧基)-5-溴苯基](4-氯苯基)甲酮
Acta Crystallogr Sect E Struct Rep Online. 2013 Jan 1;69(Pt 1):o70. doi: 10.1107/S1600536812049756. Epub 2012 Dec 12.
化学晶体学中的结构验证
Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55. doi: 10.1107/S090744490804362X. Epub 2009 Jan 20.
4
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.