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3
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Risk factors and management of dehiscent wounds in implant dentistry.
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使用抑菌圈试验评估薇乔加强缝线（含三氯生的涂层聚乙醇酸910）的体外抗菌效果。

In vitro antibacterial efficacy of Vicryl Plus suture (coated Polyglactin 910 with triclosan) using zone of inibition assays.

作者信息

Marzo G, Loffredi R, Marchetti E, DI Martino S, DI Pietro C, Marinelli G

出版信息

Oral Implantol (Rome). 2008 Apr;1(1):43-8. Epub 2008 Jun 16.

PMID:23285335
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3476502/
Abstract

OBJECTIVES

This study evaluates the in vitro antimicrobial efficacy, of an absorbable suture coated with triclosan (Vicryl Plus(®)) against two bacteria, potential responsible for the development of oral diseases: Pseudomonas aeruginosa and Streptococcus mutans.

METHODS

Vicryl Plus 3-0 and Vicryl 3-0 were tested for their efficiency against P. aeruginosa and S. Mutans. 27 segments 10 cm long each, of every suture, have been tested against P. Aeruginosa and S. Mutans respectively. Every sample has been dipped in a broth culture containing pure dried stocks of P. aeruginosa and S. mutans and placed in a Petri dish right after. Four hours later the sutures have been aseptically removed and placed in a selective culture. The incubation time was 18 hours for P. aeruginosa and 43 hours for S. mutans at 37°C. The antimicrobial efficacy of both sutures was performed by measuring the length of the bacteria-free suture segment.

RESULTS

A statistically significant difference between Vicryl Plus 3-0 and Vicryl 3-0 has been observed, with an higher bacterial growth on Vicryl 3-0 for both bacteria (P. aeruginosa and S. mutans).

CONCLUSIONS

Vicryl Plus presented an antibacterial effectiveness in vitro against both P. aeruginosa and S. mutans.

摘要

目的

本研究评估涂有三氯生的可吸收缝线（薇乔加强缝线（®））对两种可能导致口腔疾病的细菌——铜绿假单胞菌和变形链球菌的体外抗菌效果。

方法

测试薇乔加强缝线3-0和薇乔缝线3-0对铜绿假单胞菌和变形链球菌的抗菌效果。每种缝线各取27段，每段长10厘米，分别针对铜绿假单胞菌和变形链球菌进行测试。每个样本浸入含有铜绿假单胞菌和变形链球菌纯干燥菌液的肉汤培养物中，随后立即置于培养皿中。4小时后，无菌取出缝线并置于选择性培养基中。在37°C条件下，铜绿假单胞菌的培养时间为18小时，变形链球菌为43小时。通过测量无菌缝线段的长度来评估两种缝线的抗菌效果。

结果

观察到薇乔加强缝线3-0和薇乔缝线3-0之间存在统计学显著差异，两种细菌（铜绿假单胞菌和变形链球菌）在薇乔缝线3-0上的细菌生长更多。

结论

薇乔加强缝线在体外对铜绿假单胞菌和变形链球菌均具有抗菌效果。