Cecchetti F, Luciani F, Bramanti E, Bartuli F N, Ottria L, Arcuri C
DDS, "S. Giovanni Calibita - Fatebenefratelli" Hospital, University of Rome "Tor Vergata" - Department of Periodontics.
Oral Implantol (Rome). 2010 Jan;3(1):33-7. Epub 2010 Nov 19.
Fibro-osseous neoplasm remains somewhat controversial, and differing concept have been advanced regarding their nature and the proper terminology for them. Cemento-ossyfying fibroma juvenile (JOF) is a rare type of fibro-osseous tumor as also been included under the "umbrella" of cemento-ossyfying fibroma. The JOF is most often seen in patients who are between 5 and 15 years of age. With this work we emphasize the importance of a correct diagnostic approach. MATERIAL AND METHODS.: The case describes a form of cemento-ossyfying fibroma hight active and aggressive like JOF. The patient thirteen older showed from 2004 to 2008 three times the palatal lesion, it was performed with a incisional biopsy and excisional biopsy. The tumor were fixed in 10% buffered formalin embedded in paraffin cut into thick sections and stained with ematoxylineosin.
The incisional biopsy was inadequate to formulate a correct diagnosis. The histological exams have showed for three times different aspects.
Some authors in the past have suggested different classification. The COFs show different clinical, histological and radiographical patterns.
纤维-骨肿瘤仍存在一定争议，关于其性质和合适的术语，人们提出了不同的概念。青少年骨化性纤维瘤（JOF）是一种罕见的纤维-骨肿瘤，也被纳入骨化性纤维瘤的“范畴”。JOF最常见于5至15岁的患者。通过这项工作，我们强调正确诊断方法的重要性。
该病例描述了一种像JOF一样具有高活性和侵袭性的骨化性纤维瘤形式。该13岁患者在2004年至2008年期间腭部病变出现了三次，分别进行了切开活检和切除活检。肿瘤用10%缓冲福尔马林固定，石蜡包埋，切成厚切片，并用苏木精-伊红染色。
切开活检不足以做出正确诊断。组织学检查三次显示出不同的情况。
过去一些作者提出了不同的分类。骨化性纤维瘤表现出不同的临床、组织学和影像学特征。
