伊朗南部慢性血液透析患者中耐万古霉素肠球菌定植情况及其危险因素（2005 - 2006年）
Vancomycin-Resistant Entrococci colonization in chronic hemodialysis patients and its risk factors in southern Iran (2005-2006).
作者信息
Shaghaghian S, Pourabbas B, Alborzi A, Askarian M, Mardaneh J
机构信息
Community department of Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
Iran Red Crescent Med J. 2012 Oct;14(10):686-91. Epub 2012 Oct 30.
Abstract
BACKGROUND
Vancomycin-resistant enterococci (VRE) recently have emerged as a nosocomial pathogen among dialysis patients. This study aims to appraise the prevalence, incidence density and risk factors for VRE colonization among these patients.
METHODS
In this prospective study, 782 stool or rectal swab specimens were collected from 250 chronic hemodialysis patients with an interval of at least one month. To identify the risk factors of VRE colonization, demographic and health data of VRE+ and VRE- patients were compared.
RESULTS
VRE colonization was detected in 55 (22%) patients during study. Incidence density of one case per 79.6 patient-month of follow up was estimated.The only significant difference between the data collected from VRE+ and VRE- patients was observed in antibiotic consumption (P<0.001).
CONCLUSION
VRE colonization is relatively high and rapidly spreading among chronic dialysis patients. It is strongly associated with recently antibiotic consumption.
摘要
背景
耐万古霉素肠球菌（VRE）最近已成为透析患者中的一种医院病原体。本研究旨在评估这些患者中VRE定植的患病率、发病密度和危险因素。
方法
在这项前瞻性研究中，从250例慢性血液透析患者中收集了782份粪便或直肠拭子标本，间隔至少1个月。为了确定VRE定植的危险因素，比较了VRE阳性和VRE阴性患者的人口统计学和健康数据。
结果
在研究期间，55例（22%）患者检测到VRE定植。估计随访79.6患者月中有1例发病密度。从VRE阳性和VRE阴性患者收集的数据之间唯一显著差异在于抗生素使用情况（P<0.001）。
结论
VRE定植在慢性透析患者中相对较高且迅速传播。它与近期抗生素使用密切相关。
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本文引用的文献
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