Wu Hong-Mei, Guo Yu, Zhou Peng
School of Chemical and Environmental Engineering, Liaoning University of Technology, Jinzhou 121001, China.
Guang Pu Xue Yu Guang Pu Fen Xi. 2012 Oct;32(10):2722-5.
A novel dansyl sulfonamide-based fluorescence probe DH1 [(E)-5-(dimethylamino)-N-(4-(2-(quinolin-2-ylmethylene) hydrazinecarbonyl) phenyl)aphthalene-1-sulfonamide] was synthesized for detection of Zn2+. Spectral properties of DH1 such as UV-Vis, fluorescence spectra and ESI-MS for recognition of Zn2+ were studied. Spectrophotometric titration and ESI-MS spectra indicate the formation of a 1:1 complex of Zn2+ with DH1. The results show that DH1 has high quantum yield of 0.53 and low the detection limit of 1.0 x 10(-7) mol X L(-1) for detection of Zn2+ in acetonitrile/water (9:1, volume ratio). Moreover, no fluorescence intensity changes were observed in the presence of other common metal ions such as K+, Li+ , Na+, Mg2+, Ca2+, Cr3+, Mn2+, Ni2+, Pb2+, Cu2+, Cd2+, Co2+, Fe2+ and Hg2+, indicating that DH1 has excellent selectivity and high sensitivity for detection of Zn2+.
合成了一种基于丹磺酰胺的新型荧光探针DH1 [（E）-5-（二甲氨基）-N-（4-（2-（喹啉-2-基亚甲基）肼羰基）苯基）萘-1-磺酰胺]用于检测Zn2+。研究了DH1用于识别Zn2+的光谱性质，如紫外可见光谱、荧光光谱和电喷雾电离质谱。分光光度滴定和电喷雾电离质谱光谱表明Zn2+与DH1形成了1:1的配合物。结果表明，在乙腈/水（体积比9:1）中检测Zn2+时，DH1具有0.53的高量子产率和1.0×10（-7）mol·L（-1）的低检测限。此外，在存在其他常见金属离子如K+、Li+、Na+、Mg2+、Ca2+、Cr3+、Mn2+、Ni2+、Pb2+、Cu2+、Cd2+、Co2+、Fe2+和Hg2+的情况下，未观察到荧光强度变化，表明DH1对检测Zn2+具有优异的选择性和高灵敏度。
