Department of Otolaryngology Head and Neck Surgery, Affiliated Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Chin Med J (Engl). 2013 Jan;126(1):16-21.
It is believed that defects in upper airway neuromuscular control play a role in sleep apnea pathogenesis. Currently, there is no simple and non-invasive method for evaluating neuromuscular activity for the purpose of screening in patients with obstructive sleep apnea. This study was designed to assess the validity of chin surface electromyography of routine polysomnography in evaluating the neuromuscular activity of obstructive sleep apnea subjects and probe the neuromuscular contribution in the pathogenesis of the condition.
The chin surface electromyography of routine polysomnography during normal breathing and obstructive apnea were quantified in 36 male patients with obstructive sleep apnea. The change of chin surface electromyography from normal breathing to obstructive apnea was expressed as the percent compensated electromyography value, where the percent compensated electromyography value = (normal breath surface electromyography - apnea surface electromyography)/normal breath surface electromyography, and the percent compensated electromyography values among subjects were compared. The relationship between sleep apnea related parameters and the percent compensated electromyography value was examined.
The percent compensated electromyography value of the subjects varied from 1% to 90% and had a significant positive correlation with apnea hypopnea index (R(2) = 0.382, P < 0.001).
Recording and analyzing chin surface electromyography by routine polysomnography is a valid way of screening the neuromuscular activity in patients with obstructive sleep apnea. The neuromuscular contribution is different among subjects with obstructive sleep apnea.
人们认为上呼吸道神经肌肉控制的缺陷在睡眠呼吸暂停的发病机制中起作用。目前，尚无用于评估阻塞性睡眠呼吸暂停患者神经肌肉活性的简单、非侵入性方法用于筛查。本研究旨在评估常规多导睡眠图中的颏面肌电图评估阻塞性睡眠呼吸暂停患者神经肌肉活性的有效性，并探讨神经肌肉在该病症发病机制中的作用。
对 36 例男性阻塞性睡眠呼吸暂停患者进行常规多导睡眠图的正常呼吸和阻塞性呼吸暂停时颏面肌电图的量化分析。用正常呼吸颏面肌电图与阻塞性呼吸暂停颏面肌电图的差值除以正常呼吸颏面肌电图来表示颏面肌电图的补偿百分比，比较各患者的补偿百分比。检查睡眠呼吸暂停相关参数与补偿百分比的关系。
患者的补偿百分比从 1%到 90%不等，与呼吸暂停低通气指数呈显著正相关（R²=0.382，P<0.001）。
通过常规多导睡眠图记录和分析颏面肌电图是筛查阻塞性睡眠呼吸暂停患者神经肌肉活性的有效方法。阻塞性睡眠呼吸暂停患者的神经肌肉贡献不同。
