Balbo Noélia A, Acosta Maria A, Kevorkof Gregorio V
Rev Fac Cien Med Univ Nac Cordoba. 2012;69(2):83-9.
Chronic Obstructive Pulmonary Disease (COPD) leads to disability, being long-term oxygen therapy (LTOT) fundamental in final stages. It is important to assess its impact on patient's daily life.
To describe factors that determine the quality of life in COPD patients with LTOT, taking into account demographic variables: age and sex, Physiological: POST BD FEV1, BMI, hours of use of OCD and SpO2, Psychological: Dyspnea: St. George's questionnaire (SGRQ ) and Hospital Anxiety and depression Scale.
Observational, cross. 26 patients were included without associated comorbidities.
73.07% male, age: 61.73 ± 1.48 years, the average hours of use of LTOT was equal to 18.88 ± 0.77 hours, the average post-BD FEV 1 was 34.23 ± 2.63%. More anxiety and depression were observed among females. Age had an inverse correlation with the lung function but it had positive lineal correlation with the perception of dyspnea. There was less perception of dyspnea with more hours of use of LTOT. Statistical significance was achieved for the perception of dyspnea and post BD FEV1 as well as with perception of dyspnea and anxiety /depression (p< 0.05).
Anxiety and depression are highly prevalent symptoms in patients with severe COPD that also use LTOT, being higher in women. We stress the importance of using validated scales of quality of life and mental health status, to assess the overall impact of disease and optimize the treatment.
慢性阻塞性肺疾病（COPD）会导致残疾，长期氧疗（LTOT）是终末期的基本治疗方法。评估其对患者日常生活的影响很重要。
考虑人口统计学变量（年龄和性别）、生理变量（支气管扩张剂后第一秒用力呼气容积（POST BD FEV1）、体重指数（BMI）、氧疗使用时长和血氧饱和度（SpO2））以及心理变量（呼吸困难：圣乔治问卷（SGRQ）和医院焦虑抑郁量表），描述决定接受长期氧疗的COPD患者生活质量的因素。
观察性、横断面研究。纳入26例无相关合并症的患者。
男性占73.07%，年龄为61.73±1.48岁，长期氧疗的平均使用时长为18.88±0.77小时，支气管扩张剂后第一秒用力呼气容积平均为34.23±2.63%。女性中观察到更多焦虑和抑郁。年龄与肺功能呈负相关，但与呼吸困难感知呈正线性相关。长期氧疗使用时长越多，呼吸困难感知越少。呼吸困难感知与支气管扩张剂后第一秒用力呼气容积以及呼吸困难感知与焦虑/抑郁之间均具有统计学意义（p<0.05）。
焦虑和抑郁是重度COPD且接受长期氧疗患者中非常普遍的症状，在女性中更高。我们强调使用经过验证的生活质量和心理健康状况量表来评估疾病的总体影响并优化治疗的重要性。
