Foerster E C, Matek W, Hoepffner N, Domschke W
Medizinische Klinik I mit Poliklinik, Universität Erlangen-Nürnberg.
Dtsch Med Wochenschr. 1990 Apr 27;115(17):648-52. doi: 10.1055/s-2008-1065060.
Self-expanding, wire-mesh stents, 10 mm in diameter, were implanted retrogradely through the papilla of Vater via an endoscopically introduced catheter system in 14 patients (9 females, 5 males, mean age 70.2 [44-85] years) with stenosis of the common bile duct by malignant tumour. Postimplantation examinations revealed no complications caused by the stent. Two of the patients have since died from their underlying disease, the others have survived an average of 10.8 weeks with markedly reduced clinical symptoms, neither jaundice nor signs of cholestasis having recurred. Serum bilirubin concentration had fallen from a mean of 8.2 mg/dl to 1.7 mg/dl 12 weeks after the procedure. Serum alkaline phosphatase activity had similarly fallen, from 515 to 330 U/l. No increase in serum amylase activity was recorded, either initially or in the course of follow-up.
通过内镜引入的导管系统，将直径10毫米的自膨式金属丝网支架经十二指肠乳头逆行植入14例（9例女性，5例男性，平均年龄70.2岁[44 - 85岁]）因恶性肿瘤导致胆总管狭窄的患者体内。植入后检查未发现支架引起的并发症。其中2例患者随后死于基础疾病，其他患者平均存活10.8周，临床症状明显减轻，黄疸和胆汁淤积体征均未复发。术后12周，血清胆红素浓度从平均8.2毫克/分升降至1.7毫克/分升。血清碱性磷酸酶活性也同样下降，从515降至330 U/L。在初始阶段或随访过程中，均未记录到血清淀粉酶活性升高。
